Results 91 to 100 of about 666 (103)

Molecular, serological and in vitro culture-based characterization of Bourbon virus, a newly described human pathogen of the genus Thogotovirus [PDF]

open access: yesJournal of Clinical Virology, 2015
In June of 2014, a previously healthy man from Kansas with a recent history of tick exposure died from complications related to an illness marked by fever, thrombocytopenia and leukopenia. An isolate was derived from the blood of this patient during the course of diagnostic testing.
Aaron Brault   +2 more
exaly   +3 more sources

Sinu virus, a novel and divergent orthomyxovirus related to members of the genus Thogotovirus isolated from mosquitoes in Colombia

open access: yesVirology, 2017
The genome and structural organization of a novel insect-specific orthomyxovirus, designated Sinu virus, is described. Sinu virus (SINUV) was isolated in cultures of C6/36 cells from a pool of mosquitoes collected in northwestern Colombia. The virus has six negative-sense ssRNA segments. Genetic analysis of each segment demonstrated the presence of six
Vsevolod Popov   +2 more
exaly   +4 more sources

Segment-specific promoter activity for RNA synthesis in the genome of Oz virus, genus Thogotovirus

open access: yesVirology
Abstract Oz virus (OZV), a tick-borne, six-segmented negative-strand RNA virus in the genus Thogotovirus, caused a fatal human infection in Japan in 2023. To investigate mechanisms of viral RNA synthesis, we developed an OZV minigenome assay used in mammalian cells.
Lipi Akter, Ryo Matsumura
exaly   +3 more sources
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DHORI VIRUS (ORTHOMYXOVIRIDAE: THOGOTOVIRUS) INFECTION IN MICE: A MODEL OF THE PATHOGENESIS OF SEVERE ORTHOMYXOVIRUS INFECTION

American Journal of Tropical Medicine and Hygiene, 2007
After intranasal, subcutaneous, or intraperitoneal infection with Dhori virus (DHOV), adult mice developed a fulminant and uniformly fatal illness with many of the clinical and pathologic findings seen in mice infected with H5N1 highly pathogenic avian influenza A virus.
, Amelia P A Travassos Da Rosa
exaly   +3 more sources

Dhori Virus (Orthomyxoviridae: Thogotovirus) Infection of Mice Produces a Disease and Cytokine Response Pattern Similar to That of Highly Virulent Influenza A (H5N1) Virus Infection in Humans

The American Journal of Tropical Medicine and Hygiene, 2008
Mice infected with Dhori virus (DHOV) develop a fulminant, systemic, and uniformly fatal illness that has many of the clinical and pathologic findings seen in H5N1 influenza A virus infection. However, the role of host’s immune response in DHOV infection remains unclear. In this study, the concentrations of 23 inflammatory cytokines and chemokines were
Guangyu, Li   +7 more
openaire   +2 more sources

Thogotovirus

2006
Haller, Otto, Kochs, Georg
openaire   +2 more sources

Comparative Study of Ten Thogotovirus Isolates and Their Distinct In Vivo Characteristics

Journal of Virology, 2022
Martin Holzer   +2 more
exaly  

Corrigendum to ‘Sinu virus, a novel and divergent orthomyxovirus related to members of the genus Thogotovirus isolated from mosquitoes in Colombia’ [Virology 501 (2017) 166–175]

Virology, 2017
María Angélica, Contreras-Gutiérrez   +10 more
openaire   +2 more sources

Experimental Infection of Amblyomma americanum (Acari: Ixodidae) With Bourbon Virus (Orthomyxoviridae: Thogotovirus)

Journal of Medical Entomology, 2021
Angela Bosco-Lauth   +2 more
exaly  

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