Results 1 to 10 of about 52,980 (296)

Giant Thoracic Aortic Aneurysm Rupture in a Patient with Extensive Atherosclerotic Disease [PDF]

Journal of the Belgian Society of Radiology
Aneurysmal dilatations can affect any aortic segment and represent the result of various causes, atherosclerotic disease being the most common and frequently involved.
Ramona Mihaela Popa, Chiriță Andrei-Constantin, Rosana Mihaela Manea   +2 more
doaj   +2 more sources

Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the second most prevalent aortic disease following atherosclerosis, representing the ninth‐leading cause of death globally. Open surgery and endovascular procedures are
Haocheng Lu, Wa Du, Lu Ren, Milton H. Hamblin, Richard C. Becker, Y. Eugene Chen, Yanbo Fan   +6 more
doaj   +1 more source

Emergency rescue stent grafting for a ruptured degenerated graft that bypassed coarctation of the aorta: a case report [PDF]

Kosin Medical Journal, 2022
A 33-year-old man who had undergone bypass from the distal aortic arch to the proximal descending thoracic aorta with a Dacron graft to treat coarctation of the aorta 20 years prior presented to the emergency department with massive hemoptysis.
Jin Ho Choi, Min Suk Choi, Haeyoung Lee
doaj   +1 more source

Fluid-structure instability forecasts thoracic aortic aneurysm progression [PDF]

Nat. Biomed. Eng 7, 1614-1626 (2023), 2021
The basic mechanism driving aneurysm growth is unknown. Currently, clinical diagnosis of an aneurysm is mainly informed by retrospective tracking of its size and growth rate. However, aneurysms can rupture before reactive criteria are met or remain stable when they are exceeded.
arxiv   +1 more source

Mathematical modeling of shear-activated targeted nanoparticle drug delivery for the treatment of aortic diseases [PDF]

Biomechanics and Modeling in Mechanobiology (2021), 2021
The human aorta is a high-risk area for vascular diseases, which are commonly restored by thoracic endovascular aortic repair. In this paper, we report a promising shear-activated targeted nanoparticle drug delivery strategy to assist in the treatment of coarctation of the aorta and aortic aneurysm.
arxiv   +1 more source

Hemodynamic effects of stent-graft introducer sheath during thoracic endovascular aortic repair [PDF]

Biomechanics and Modeling in Mechanobiology (2022), 2021
Thoracic endovascular aortic repair (TEVAR) has become the standard treatment of a variety of aortic pathologies. The objective of this study is to evaluate the hemodynamic effects of stent-graft introducer sheath during TEVAR. Three idealized representative diseased aortas of aortic aneurysm, coarctation of the aorta, and aortic dissection were ...
arxiv   +1 more source

Familial Bainbridge‐Ropers syndrome: Report of familial ASXL3 inheritance and a milder phenotype

American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 29-36, January 2023., 2023
Abstract De novo truncating and splicing pathogenic variants in the Additional Sex Combs‐Like 3 (ASXL3) gene are known to cause neurodevelopmental delay, intellectual disability, behavioral difficulties, hypotonia, feeding problems and characteristic facial features.
Schaida Schirwani, Emily Woods, David A. Koolen, Charlotte W. Ockeloen, Sally Ann Lynch, Karl Kavanagh, John M. Graham Jr, Katheryn Grand, Tyler Mark Pierson, Jeffrey M. Chung, Meena Balasubramanian   +10 more
wiley   +1 more source

Comprehensive genetic screening for vascular Ehlers–Danlos syndrome through an amplification‐based next‐generation sequencing system

American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 37-51, January 2023., 2023
Abstract Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder (HCTD) characterized by arterial dissection/aneurysm/rupture, sigmoid colon rupture, or uterine rupture. Diagnosis is confirmed by detecting heterozygous variants in COL3A1.
Tomomi Yamaguchi, Shujiro Hayashi, Daisuke Hayashi, Takeshi Matsuyama, Norimichi Koitabashi, Kenichi Ogiwara, Masaaki Noda, Chiai Nakada, Shinya Fujiki, Akira Furutachi, Yasuhiko Tanabe, Michiko Yamanaka, Aki Ishikawa, Miyako Mizukami, Asako Mizuguchi, Kazumitsu Sugiura, Makoto Sumi, Hirokuni Yamazawa, Atsushi Izawa, Yuko Wada, Tomomi Fujikawa, Yuri Takiguchi, Keiko Wakui, Kyoko Takano, Shin‐Ya Nishio, Tomoki Kosho   +25 more
wiley   +1 more source

Isolated aneurysmal disease as an underestimated finding in individuals with JAG1 pathogenic variants

Human Mutation, Volume 43, Issue 12, Page 1824-1828, December 2022., 2022
Abstract Pathogenic variants in JAG1 are known to cause Alagille syndrome (ALGS), a disorder that primarily affects the liver, lung, kidney, and skeleton. Whereas cardiac symptoms are also frequently observed in ALGS, thoracic aortic aneurysms have only been reported sporadically in postmortem autopsies.
Jotte Rodrigues Bento, Alice Krebsová, Ilse Van Gucht, Irene Valdivia Callejon, An Van Berendoncks, Pavel Votypka, Ilse Luyckx, Petra Peldova, Steven Laga, Marek Havelka, Lut Van Laer, Pavel Trunecka, Nele Boeckx, Aline Verstraeten, Milan Macek, Josephina A. N. Meester, Bart Loeys   +16 more
wiley   +1 more source

Ortner’s syndrome secondary to thoracic aortic aneurysm: a case series

Journal of Cardiothoracic Surgery, 2022
Background Ortner’s syndrome refers to vocal cord paralysis resulting from compression of the left recurrent laryngeal nerve by abnormal mediastinal vascular structures.
Zhiwen Zhang, Hai Feng, Xueming Chen, Wenrui Li   +3 more
doaj   +1 more source