Results 1 to 10 of about 129,714 (272)

Thoracic aortic aneurysm [PDF]

Vascular Medicine, 2018
An aneurysm occurs when the walls of a blood vessel weaken, causing it to enlarge or dilate. Aneurysms can form in any blood vessel in the body, but they are most common in the aorta.1 The aorta is the main blood vessel that arises from the heart and ...
M. Salameh, J. Black, E. Ratchford
semanticscholar   +4 more sources

Giant Thoracic Aortic Aneurysm Rupture in a Patient with Extensive Atherosclerotic Disease [PDF]

Journal of the Belgian Society of Radiology
Aneurysmal dilatations can affect any aortic segment and represent the result of various causes, atherosclerotic disease being the most common and frequently involved.
Ramona Mihaela Popa, Chiriță Andrei-Constantin, Rosana Mihaela Manea   +2 more
doaj   +2 more sources

A review of thoracic aortic aneurysm disease [PDF]

Echo Research & Practice, 2019
Aortic diseases may be diagnosed after a long period of subclinical development or they may have an acute presentation. Acute aortic syndrome is often the first sign of the disease, which needs rapid diagnosis and decision making to reduce the extremely ...
P. Clift, E. Cervi
semanticscholar   +4 more sources

Targeting endothelial tight junctions to predict and protect thoracic aortic aneurysm and dissection.

European Heart Journal, 2023
AIMS Whether changes in endothelial tight junctions (TJs) lead to the formation of thoracic aortic aneurysm and dissection (TAAD) and serve as an early indicator and therapeutic target remains elusive.
Xueyuan Yang, Chen Xu, Fang Yao, Qianhui Ding, Hao Liu, Congcong Luo, Daidai Wang, Jiaqi Huang, Zhiqing Li, Yicong Shen, Weimin Yang, Zhuofan Li, F. Yu, Yi Fu, Li Wang, Qingbian Ma, Junming Zhu, Fujian Xu, X. Cong, W. Kong   +19 more
semanticscholar   +1 more source

Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the second most prevalent aortic disease following atherosclerosis, representing the ninth‐leading cause of death globally. Open surgery and endovascular procedures are
Haocheng Lu, Wa Du, Lu Ren, Milton H. Hamblin, Richard C. Becker, Y. Eugene Chen, Yanbo Fan   +6 more
doaj   +1 more source

Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program

Nature Genetics, 2023
The current understanding of the genetic determinants of thoracic aortic aneurysms and dissections (TAAD) has largely been informed through studies of rare, Mendelian forms of disease.
D. Klarin, P. Devineni, A. Sendamarai, Anthony R. Angueira, Sarah E. Graham, Ying H. Shen, M. Levin, J. Pirruccello, I. Surakka, P. Karnam, Tanmoy Roychowdhury, Yanming Li, Minxian Wang, Krishna G. Aragam, K. Paruchuri, V. Zuber, Gabrielle Shakt, N. Tsao, R. Judy, H. M. T. Vy, S. Verma, D. Rader, R. Do, J. Bavaria, G. Nadkarni, M. Ritchie, S. Burgess, Dong-chuan Guo, P. Ellinor, S. Lemaire, D. Milewicz, C. Willer, P. Natarajan, P. Tsao, S. Pyarajan, S. Damrauer   +35 more
semanticscholar   +1 more source

The emerging role of endothelial cells in the pathogenesis of thoracic aortic aneurysm and dissection

European Heart Journal, 2023
Graphical Abstract Graphical Abstract Schematic overview of the different important endothelial signaling pathways and molecular processes involved in the pathogenesis of thoracic aortic aneurysm and ...
A. Verstraeten, Ivanna Fedoryshchenko, B. Loeys   +2 more
semanticscholar   +1 more source

Emergency rescue stent grafting for a ruptured degenerated graft that bypassed coarctation of the aorta: a case report [PDF]

Kosin Medical Journal, 2022
A 33-year-old man who had undergone bypass from the distal aortic arch to the proximal descending thoracic aorta with a Dacron graft to treat coarctation of the aorta 20 years prior presented to the emergency department with massive hemoptysis.
Jin Ho Choi, Min Suk Choi, Haeyoung Lee
doaj   +1 more source

Single-cell RNA sequencing identifies an Il1rn+/Trem1+ macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissection

Cell Discovery, 2022
Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening condition characterized by medial layer degeneration of the thoracic aorta. A thorough understanding of the regulator changes during pathogenesis is essential for medical therapy ...
Xuanyu Liu, Wen Chen, Guoyan Zhu, Hang Yang, Wenke Li, M. Luo, Chang Shu, Zhou Zhou   +7 more
semanticscholar   +1 more source

The Genetics and Typical Traits of Thoracic Aortic Aneurysm and Dissection.

Annual review of genomics and human genetics (Print), 2022
Genetic predisposition and risk factors such as hypertension and smoking can instigate the development of thoracic aortic aneurysm (TAA), which can lead to highly lethal aortic wall dissection and/or rupture.
J. Rodrigues Bento, J. Meester, I. Luyckx, Silke Peeters, A. Verstraeten, B. Loeys   +5 more
semanticscholar   +1 more source