Results 31 to 40 of about 31,143 (238)

Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level

Frontiers in Pharmacology, 2023
Introduction: Aortic aneurysm is a life-threatening disease resulted from progressive dilatation of the aorta, which can be subdivided into thoracic and abdominal aortic aneurysms.
Hong Wu, Cheng Xie, Ruilin Wang, Jun Cheng, Qingbo Xu, Haige Zhao   +5 more
doaj   +1 more source

Mitochondrial function in thoracic aortic aneurysms [PDF]

Cardiovascular Research, 2018
Mitochondria contain multiple copies of mitochondrial DNA (mtDNA) that encode ribosomal and transfer RNAs and many essential proteins required for oxidative phosphorylation. Mitochondria are essential for generation of ATP, but also generate reactive oxygen species (ROS) as a by-product of the electron transport chain. Oxidative damage to mitochondrial
Bennett, MR, Yu, Emma, Foote, kirsty
openaire   +2 more sources

MicroRNAs in ascending thoracic aortic aneurysms [PDF]

Bioscience Reports, 2020
AbstractThoracic Aortic Aneurysm (TAA) is characterized by the dilation of the aorta and is fatal if not diagnosed and treated appropriately. The underlying genetic mechanisms have not been completely delineated, so better knowledge of the physiopathology of TAAs is needed to improve detection and therapy.
Areti Moushi, Nir Pillar, Anna Keravnou, Marinos Soteriou, Noam Shomron, Marios A. Cariolou, Evy Bashiardes   +6 more
openaire   +3 more sources

Acute Aortic Syndromes and Thoracic Aortic Aneurysm [PDF]

Mayo Clinic Proceedings, 2009
Acute and chronic aortic diseases have been diagnosed and studied by physicians for centuries. Both the diagnosis and treatment of aortic diseases have been steadily improving over time, largely because of increased physician awareness and improvements in diagnostic modalities.
Jae K. Oh, Vijay S. Ramanath, Kim A. Eagle, Thoralf M. Sundt   +3 more
openaire   +2 more sources

Thoracic and Abdominal Aortic Aneurysms [PDF]

Circulation, 2005
Aneurysms of the aorta are at times evaluated and treated by physicians from a number of specialties. Indeed, whereas cardiac surgeons operate on the ascending aorta and arch and vascular surgeons manage abdominal aortic aneurysms, at present the responsibility often falls to cardiologists to oversee the medical care of patients with aortic disease of ...
openaire   +2 more sources

Aortic Aneurysm with and without Dissection and Concomitant Atherosclerosis—Differences in a Retrospective Study

Journal of Cardiovascular Development and Disease
Background: Thoracic aortic aneurysm is a latent disease with a high risk of death. Today, as data are accumulating, an estimation of the differences in thoracic aneurysm in men and women of different age groups is required.
Andrey V. Suslov, Tatiana V. Kirichenko, Andrey V. Omelchenko, Petr V. Chumachenko, Alexandra Ivanova, Yury Zharikov, Yuliya V. Markina, Alexander M. Markin, Anton Yu. Postnov   +8 more
doaj   +1 more source

Secondary aortoesophageal fistula after thoracic endovascular aortic repair for a huge aneurysm

Diagnostic and Interventional Radiology, 2013
Thoracic endovascular aortic repair for a descending thoracic aortic aneurysm is an excellent alternative to open surgery, especially in patients with a number of comorbidities.
Akhmadu Muradi, Masato Yamaguchi, Atsushi Kitagawa, Yoshikatsu Nomura, Takuya Okada, Yutaka Okita, Koji Sugimoto   +6 more
doaj   +1 more source

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

Advanced Science, EarlyView.
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu, Ze‐Yu Cai, Qing‐Le Li, Tao Zhang, Xiang‐Yu Chu, Chang Wang, Qing‐Yi Zhang, Rong Qi   +7 more
wiley   +1 more source

Endovascular Stent Grafting for Aortic Arch Aneurysm in Aortoiliac Occlusive Disease following Aortic Arch Debranching and Aortobifemoral Reconstruction

Case Reports in Medicine, 2017
Treatment of thoracic aortic aneurysms constitutes high mortality and morbidity rates despite improvements in surgery, anesthesia, and technology. Endovascular stent grafting may be an alternative therapy with lower risks when compared with conventional ...
Didem Melis Oztas, Cagla Canbay, Yilmaz Onal, Metin Onur Beyaz, Omer Ali Sayin, Mehmet Barburoglu, Mehmet Buget, Mesut Yornuk, Aziz Ari, Murat Ugurlucan, Bulent Acunas, Ufuk Alpagut, Enver Dayioglu   +12 more
doaj   +1 more source

Existing and Emerging Approaches to Risk Assessment in Patients with Ascending Thoracic Aortic Dilatation

Journal of Imaging, 2022
Ascending thoracic aortic aneurysm is a life-threatening disease, which is difficult to detect prior to the occurrence of a catastrophe. Epidemiology patterns of ascending thoracic aortic dilations/aneurysms remain understudied, whereas the risk ...
Nina D. Anfinogenova, Valentin E. Sinitsyn, Boris N. Kozlov, Dmitry S. Panfilov, Sergey V. Popov, Alexander V. Vrublevsky, Alexander Chernyavsky, Tatyana Bergen, Valery V. Khovrin, Wladimir Yu. Ussov   +9 more
doaj   +1 more source