Results 111 to 120 of about 567,728 (203)

Thoracic Aortic Dissection: Are Matrix Metalloproteinases Involved?

, 2009
Thoracic aortic dissection, one of the major diseases affecting the aorta, carries a very high mortality rate. Improving our understanding of the pathobiology of this disease may help us develop medical treatments to prevent dissection and subsequent ...
Scott A. LeMaire, Ying H. Shen, Xiaoming Zhang   +2 more
core   +1 more source

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2241-2249, October 2026.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura, Tomomi Yamaguchi, Tomoki Kosho   +2 more
wiley   +1 more source

Aortic remodeling predicts long-term survival and freedom from reintervention after thoracic endovascular aortic repair for chronic type B aortic dissection including residual type A dissection

JVS-Vascular Insights
Background: The optimal timing for thoracic endovascular aortic repair in chronic type B aortic dissection is controversial, largely because the long-term impact of aortic remodeling on clinical outcomes remains unclear.
Sadanari Sawaki, MD, PhD, Mika Kumagai, MA, Kazuki Nomura, MD, Shogo Maeda, MD, Riku Kato, MD, Tsubasa Yazawa, MD, Masayoshi Tokoro, MD, PhD, Ayumi Shintani, MPH, PhD, Toshiaki Ito, MD, PhD   +8 more
doaj   +1 more source

Cancer Risk in Marfan Syndrome: A Swedish Population‐Based Cohort Study

International Journal of Cancer, Volume 159, Issue 7, Page 1707-1714, 1 October 2026.
The cancer risk in Marfan syndrome, an autosomal dominant connective tissue disorder, largely remains to be explored. In this population‐based matched cohort study of 1544 Swedish patients, the overall cancer risk in adults with Marfan syndrome showed no significant increase, except for the risk of endocrine tumours with a nearly threefold increase ...
Ida Nordgren, Anna Skarin Nordenvall, Alexandra Wachtmeister, Fulya Taylan, Yunxia Lu, Christina Norrby, Anna Lindstrand, Giedre Grigelioniene, Giorgio Tettamanti   +8 more
wiley   +1 more source

Open repair of chronic thoracic and thoracoabdominal aortic dissection using deep hypothermia and circulatory arrest

, 2017
Background Chronic dissection of the thoracic and thoracoabdominal aorta as sequela of a prior type A or B dissection is a challenging problem that requires close radiographic surveillance and prompt operative intervention in the presence of symptoms ...
Fehrenbacher, John, Hannah Copeland, Adam Hicks, Corvera, Joel, Hess, Philip, Hicks, Adam, David Blitzer, Philip Hess, Copeland, Hannah, John Fehrenbacher, Manghelli, Joshua, Joshua Manghelli, Joel Corvera, Blitzer, David   +13 more
core   +1 more source

Exploring ethnic differences in the perioperative course of thoracic aortopathy

Frontiers in Cardiovascular Medicine
BackgroundIn patients with thoracic aortopathy post-operative recovery can be complicated by a lack of consistent, clear communication and guidance. Despite the growing recognition of these challenges, the specific needs of patients undergoing aortic ...
Nora Bacour, Aytug U. Tirpan, Simran Grewal, Robert J. M. Klautz, Robert J. M. Klautz, Nimrat Grewal, Nimrat Grewal, Nimrat Grewal   +7 more
doaj   +1 more source

Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.

Journal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Background Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra.
M. E. Hensel, G. W. Wilkerson, L. Yan, C. L. Hodo, S. M. Kezar   +4 more
wiley   +1 more source

Trace Element Changes in Thoracic Aortic Dissection

, 2016
Thoracic aortic dissection is a life-threatening condition with an incompletely understood pathogenesis. Trace elements are essential for the functioning of different processes in the body, including the immune system and associated responses to ...
Frisk, Peter,, Edvinsson, Marie,, Ilbäck, Nils-Gunnar,, Nyström-Rosander, Christina,, Thelin, Stefan,   +4 more
core   +1 more source

Thermal septotomy complications and management of residual septum visceral ostial occlusions

Journal of Vascular Surgery Cases and Innovative Techniques
A 61-year-old man with a previous total arch reconstruction with frozen elephant trunk presented with an expanding descending thoracic aortic aneurysm in the setting of a residual chronic type B aortic dissection.
Christina Shields, MD, Joshua Grimm, MD, Lili Sadri, MD, Karla Moriel, MD, Joshua Crapps, MD, Samuel Leonard, MD   +5 more
doaj   +1 more source

UBE2O Drives Immune Evasion and Radioimmunotherapy Resistance in Lung Cancer by Degrading CDKL1 to Induce PD‐L1 Transcription

Advanced Science, Volume 13, Issue 52, 18 September 2026.
UBE2O targets CDKL1 for the degradation to upregulate PD‐L1 expression and promotes resistance to radioimmunotherapy in lung cancer, supporting the potential of targeting UBE2O as a promising therapeutic strategy. ABSTRACT Resistance to radioimmunotherapy is one of the primary causes of treatment failure in lung cancer patients; however, the underlying
Huichan Xue, Xiaohua Jie, Zhiwei Liu, Ruoxin Fang, Shuo Wu, Xiaorong Dong, Shuangbing Xu   +6 more
wiley   +1 more source