Results 91 to 100 of about 288,852 (258)

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

PediCXR: An open, large-scale chest radiograph dataset for interpretation of common thoracic diseases in children. [PDF]

Sci Data, 2023
Pham HH, Nguyen NH, Tran TT, Nguyen TNM, Nguyen HQ.   +4 more
europepmc   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

THORACIC SURGERY. THE SURGICAL TREATMENT OF THORACIC DISEASE

Southern Medical Journal, 1926
Mode of access: Internet.
openaire   +3 more sources

Preclinical and Toxicology Assessment of ALW-II-41-27, an Inhibitor of the Eph Receptor A2 (EphA2)

Drugs in R&D
Background and Objective The EphA2 receptor inhibitor ALW-II-41-27 has proven to be an effective in vitro antagonist of Pneumocystis β-glucan-induced proinflammatory signaling. This suggests its potential as a candidate for initial anti-inflammatory drug
Theodore J. Kottom, Kimberly E. Stelzig, Madeline R. Pellegrino, Marc Bindzus, Eunhee S. Yi, Andrew H. Limper   +5 more
doaj   +1 more source

Primary Pulmonary Synovial Sarcoma: A Very Rare Presentation

Case Reports in Pulmonology, 2014
Synovial sarcoma (SS) is a rare tumor originating from mesenchymal tissue and accounting for approximately 5–10% of all soft tissue sarcomas.
Ekrem Cengiz Seyhan, Sinem Nedime Sokucu, Gulsah Gunluoglu, Nurdan Simsek Veske, Sedat Altin   +4 more
doaj   +1 more source

Prospective evaluation of thoracic diseases using a compact flat-panel detector spiral computed tomographic scanner. [PDF]

Eur J Radiol Open, 2022
Kim DS, Yoo SJ, Hong JH, Kwak N, Yim JJ, Yoon SH.   +5 more
europepmc   +1 more source

Oligopeptides/DNA Coacervate Droplets as Macromolecular Delivery Microcarriers

Advanced Science, EarlyView.
Oligopeptide–DNA coacervates formed via liquid–liquid phase separation serve as programmable carriers for macromolecular cargos, entering cells through lipid raft–associated pathways and subsequently undergoing enzyme triggered intracellular disassembly driven by DNA degradation processes, thereby enabling efficient, controlled, and spatially defined ...
Linyi Zhang, Chong Wang, Mengqi Han, Yi Yang, Teng Ma, Luoran Shang   +5 more
wiley   +1 more source

Is It Safe to Omit Any Chest X‐Ray Before Removing the Chest Drain After Elective, Non‐Cardiac Thoracic Surgery? A Single‐Center, Retrospective, Case–Control Study

Thoracic Cancer
Background Every patient undergoing non‐cardiac thoracic surgery will receive several chest X‐rays through the perioperative period. The patient might receive a preoperative X‐ray as a baseline as well as several X‐rays before and after drain removal ...
Ioannis Karampinis, Carolin Reker, Laura Grifone, Fabio Souschek, Christian Galata, Davor Stamenovic, Eric Roessner   +6 more
doaj   +1 more source