Results 61 to 70 of about 630,098 (253)

MetaboSense: An Integrated Quantum Dot‐Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In‐Line Monitoring of Lung Metabolism During Ex Vivo Perfusion

Advanced Science, EarlyView.
MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant, Pouyan Keshavarz Motamed, Thomas Borrillo, Lielle Ronen, Gabriel Siebiger, Guillermo Garza, Hesam Abouali, Md Fahim Al Fattah, Ines Jaber, Dayan Ban, Marcelo Cypel, Mingyao Liu, Shaf Keshavjee, Andrew T. Sage, Mahla Poudineh   +14 more
wiley   +1 more source

Critical analysis of thoracotomies performed in the emergency room in 10 years

Revista do Colégio Brasileiro de Cirurgiões
OBJECTIVE: To conduct a critical analysis of thoracotomies performed in the emergency rooms.METHODS: We analyzed mortality rates and survival as outcome variables, mechanism of injury, site of injury and anatomic injury as clinical variables, and gender ...
Marcelo Beck Guimarães, Diego Carrão Winckler, Nádia Gabriele Rudnick, Ricardo Breigeiron   +3 more
doaj   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Vascular injuries after blunt chest trauma: diagnosis and management

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2009
Background Although relatively rare, blunt injury to thoracic great vessels is the second most common cause of trauma related death after head injury.
Griffith Bartley P, Scalea Thomas M, Byrne Christopher, O'Connor James V, Neschis David G   +4 more
doaj   +1 more source

p300‐Mediated H3K18 Lactylation Drives Radiation‐Induced Pulmonary Fibrosis via VIRMA‐Dependent m6A Modification of GATA3

Advanced Science, EarlyView.
Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi, Mingwei Wang, Duo Yu, Mingqi Zhao, Xinyan Wang, Shiqi Li, Xiaowen Han, Wei Wei, Shunzi Jin   +8 more
wiley   +1 more source

Endovascular repair for complicated Azzizadeh Grade III blunt traumatic aortic injury: a single-center cohort study of thoracic injuries with a separate abdominal subgroup

BMC Cardiovascular Disorders
Background The optimal management of Azzizadeh Grade III blunt traumatic aortic injury (BTAI) is debated, with a clinical dilemma persisting particularly for hemodynamically stable patients.
Chaoyao Hou, Zhikai Xu, Chuntao Wang
doaj   +1 more source

Neurological Recovery Following Surgical Intervention in Patients with Traumatic Spinal Cord Injury at the University Teaching Hospital in Zambia

Journal of Spine Practice
Introduction Traumatic spinal cord injuries cause long-term disability and functional impairment. Timely and proper surgical treatment improves neurological recovery and functional outcomes.
Munosiya Mulemwa, Joseph Lupenga, Martha Banda-Chalwe   +2 more
doaj   +1 more source

Pattern of Thoracic Injuries in Patients Admitted to Cardiothoracic Department at New Damietta Hospital, Al-Azhar University [PDF]

Al-Azhar International Medical Journal
Background: Thoracic injuries constitute a significant public health challenge worldwide. They are a major cause of morbidity and mortality, especially among young males and rural populations.
shaimaa daador, Nagy Alfadaly, Gamal Farag, Samir Elmetwally   +3 more
doaj   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Contemporary Thoracic Aortic and Abdominal Injuries: An Emergency Strategy.

, 2017
To the Editor: Topcu and colleagues [1] interestingly bring attention to the management of contemporary injury of the thoracic aorta and spleen. On the basis of our experience, we would like to consider some basic points.
BARBIERI, Alberto, Antonio Manenti, Gabriele Melegari, Maurizio Zizzo, Zizzo, Maurizio, Alberto Barbieri, MANENTI, Antonio, Melegari, Gabriele   +7 more
core   +1 more source