Results 91 to 100 of about 90,511 (304)

Navigating the Post‐BCMA/GPRC5D Landscape: Efficacy of Selinexor, Bortezomib, and Dexamethasone After Sequential Immunotherapy Failure in Penta‐Refractory Multiple Myeloma—A Multicenter Analysis

American Journal of Hematology, EarlyView.
ABSTRACT Patients with relapsed/refractory multiple myeloma (RRMM) who are penta‐drug refractory, defined as resistant to two proteasome inhibitors, two immunomodulatory agents, and an anti‐CD38 monoclonal antibody, face a dismal prognosis, particularly after exposure to T‐cell–redirecting therapies.
Maximilian Al‐Bazaz, Winfried Alsdorf, Lisa Leypoldt, Piet Sonnemann, Christoph Schaefers, Jule Artzenroth, Marie Harzer, Abdulaziz Kamili, Leandra Bartke, Leon Cords, Jan Vorwerk, Theo Leitner, Markus Maulhardt, Kerstin Brinkert, Annamaria Brioli, Tim Richardson, Udo Holtick, Stefan M. Hillmann, Hans Salwender, Cyrus Khandanpour, Carsten Bokemeyer, Katja Weisel, Ricardo Kosch   +22 more
wiley   +1 more source

EGFR mutation positive stage IV non small-cell lung cancer: treatment beyond progression [PDF]

, 2014
Non-small-cell lung cancer (NSCLC) is the leading cause of death from cancer for both men en women. Chemotherapy is the mainstay of treatment in advanced disease, but is only marginally effective. In about 30% of patients with advanced NSCLC in East Asia
Ferdinande, Liesbeth, Lievens, Yolande, Surmont, Veerle, VAN ASSCHE, KATRIJN, Vandecasteele, Katrien   +4 more
core   +3 more sources

Silicosis, Sarcoidosis, and Silicosarcoidosis Are Overlapping Diagnoses and Difficult to Differentiate

American Journal of Industrial Medicine, EarlyView.
ABSTRACT We evaluated 12 workers with documented exposure to respirable crystalline silica who were referred to a tertiary care center due to clinical suspicion of silicosis, sarcoidosis, or silicosarcoidosis. Although silica exposure is a well‐established risk factor for silicosis and has been associated with autoimmune diseases, mycobacterial ...
Guilherme Ward Leite, Eduardo Kaiser Ururahy Nunes Fonseca, Rodrigo Caruso Chate, Lavinia Clara Del Roio, Sofia de Paiva Memento Machado, Jefferson Benedito de Freitas, Ronaldo Adib Kairalla, Mário Terra‐Filho, Ubiratan Paula Santos, Rafael Futoshi Mizutani   +9 more
wiley   +1 more source

Efficacy and safety of early radiotherapy combined with first-line chemo-immunotherapy in extensive-stage small-cell lung cancer: a multi-center analysis

Frontiers in Immunology
BackgroundsThis study aimed to evaluate efficacy and safety of early radiotherapy combined with first-line chemo-immunotherapy in patients with extensive-stage small-cell lung cancer (ES-SCLC).MethodsES-SCLC patients treated with first-line chemo ...
Jingyi Jia, Ya Zeng, Yongling Ji, Hui Zhu, Rui Meng, Bing Xia, Yunfeng Wang, Tianle Shen, Xi Su, Tongfang Zhou, Yifei Lu, Lei Zhao, Zhangru Yang, Xiaolong Fu, Xuwei Cai   +14 more
doaj   +1 more source

Interobserver Reliability in Describing Radiographic Lung Changes After Stereotactic Body Radiation Therapy [PDF]

, 2018
Purpose Radiographic lung changes after stereotactic body radiation therapy (SBRT) vary widely between patients. Standardized descriptions of acute (≤6 months after treatment) and late (\u3e6 months after treatment) benign lung changes have been proposed
Hugo, Geoffrey D., Jan, Nuzhat, Kahn, Jenna M., Kalman, Noah S., Mahon, Rebecca N., Weiss, Elisabeth, Zhao, Sherry S.   +6 more
core   +3 more sources

Severe Occupational Hypersensitivity Pneumonitis: A Case Series of Four Patients Requiring Lung Transplantation

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Hypersensitivity pneumonitis (HP) is an immune‐mediated interstitial lung disease triggered by repeated inhalation of organic or chemical antigens. Occupational exposures account for approximately 19% of all cases. Early diagnosis, identification of the responsible antigen(s), and immediate avoidance of exposure are crucial to prevent ...
Ludwig Frei‐Stuber, Judith Mohren, Ester Mau, Bernhard Werner, Rudolf A. Hatz, Jürgen Barton, Dennis Nowak   +6 more
wiley   +1 more source

PALLIATION AND LIFE QUALITY IN LUNG-CANCER - HOW GOOD ARE CLINICIAN AT JUDGING TREATMENT OUTCOME [PDF]

, 1991
A recent trial by the MRC Lung Cancer Working Party used physician assessments to compare two palliative schedules of radiotherapy in lung cancer.
Cooke, NT, Jones, PW, Regan, J, Yarnold, J   +3 more
core   +1 more source

An Evaluation of Mortality Rates and Their Determinants in a Cohort of Former Asbestos Miners in South Africa

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background A causal association between occupational asbestos exposure and lung disease, including pneumoconiosis and mesothelioma, is well established. Elevated mortality among former asbestos miners is expected. However, large‐scale South African studies examining all‐cause mortality in this population are lacking.
Yumna Williams‐Mohamed, Rodney Ehrlich, Jim teWaterNaude, Shahieda Adams   +3 more
wiley   +1 more source

Radiation Therapy in Extensive Stage Small Cell Lung Cancer

Frontiers in Oncology, 2017
Lung cancer is the major cancer killer in the Western world, with the small cell lung cancer (SCLC) representing around 15–20% of all lung cancers. Extensive disease small cell lung cancer (ED SCLC) is found in approximately two-thirds of all cases ...
Branislav Jeremic, Antonio Gomez-Caamano, Pavol Dubinsky, Nikola Cihoric, Franesc Casas, Nenad Filipovic   +5 more
doaj   +1 more source

Safety and efficacy of stereotactic body radiation therapy in the treatment of pulmonary metastases from high grade sarcoma. [PDF]

, 2013
Introduction. Patients with high-grade sarcoma (HGS) frequently develop metastatic disease thus limiting their long-term survival. Lung metastases (LM) have historically been treated with surgical resection (metastasectomy).
Agazaryan, Nzhde, Chmielowski, Bartosz, Eilber, Fritz C, Federman, Noah, Lee, Jay M, Lee, Percy, Mehta, Niraj, Selch, Michael, Steinberg, Michael, Wang, Pin-Chieh   +9 more
core   +2 more sources