Results 111 to 120 of about 520,129 (244)

Radiation‐free or Chemo‐free: Rethinking the Best Strategy for PD‐L1‐High, Unresectable Stage III NSCLC

Precision Radiation Oncology, EarlyView.
This article discusses the emerging radiotherapy‐free and chemo‐free strategies in PD‐L1–high, unresectable stage III NSCLC, reviewing the Evolution trial and comparing it with existing treatments. We highlight the need for further research to validate these approaches and ensure safe de‐escalation without compromising ...
Yongbo Xiang, Nan Bi
wiley   +1 more source

C–X–C Motif Chemokine Receptor 4 (CXCR4)‐Targeted Biologically Guided Proton Spatially Fractionated Radiotherapy for Bulky Limited‐Stage Small Cell Lung Cancer

Precision Radiation Oncology, EarlyView.
A newly proposed proton spatially fractionated radiotherapy guided by biological imaging Abstract Background and Purpose To evaluate the feasibility and dosimetric safety of integrating C–X–C motif chemokine receptor 4 (CXCR4)‐targeted tracer 18F‐AlF‐NOTA‐QHY‐04 positron emission tomography imaging with biologically guided proton spatially fractionated
Keru Pu, Tengxiang Li, Shengnan Xu, Xue Sha, Qingtao Qiu, Jinming Yu, Yong Yin, Jie Liu   +7 more
wiley   +1 more source

Research progress of radiation-induced heart disease: from epidemiology to clinical management

Zhongguo Linchuang Yixue
Radiation-induced heart disease (RIHD) is a form of cardiotoxicity caused by radioactive substances or radiotherapy, and represents a common long-term complication after thoracic malignancy radiotherapy.
Siyu Zhu, Yihui Shen, Leilei Cheng
doaj   +1 more source

Consolidative thoracic radiotherapy in stage IV small cell lung cancer: Selection of patients amongst European IASLC and ESTRO experts.

, 2019
BACKGROUND The role of consolidative thoracic radiotherapy (TRT) in stage IV small cell lung cancer (SCLC) is not uniformly accepted. METHODS We obtained a list of 13 European medical oncologists from the International Association for the Study of ...
Troost, Esther G C, Glatzer, Markus, Widder, Joachim, Belderbos, José, de Marinis, Filippo, Reck, Martin, Nestle, Ursula, Pöttgen, Stephanie, Van Houtte, Paul, Novello, Silvia, Ramella, Sara, Dziadiuszko, Rafal, Putora, Paul Martin, Früh, Martin, Besse, Benjamin, Westeel, Virginie, De Ruysscher, Dirk, McDonald, Fiona, Peeters, Stephanie, Blackhall, Fiona, Garrido, Pilar, Felip, Enriqueta, Califano, Raffaele, Paz Ares, Luis, Slotman, Ben J, Mornex, Francoise, Le Pechoux, Cecile, Cappuzzo, Federico, Faivre-Finn, Corinne, Brien, Mary O'   +29 more
core   +1 more source

Preoperative educational materials improve the short‐term quality of life of patients with urinary cancer

UroPrecision, EarlyView.
Abstract Background This study aimed to evaluate the short‐term influence of preoperative educational materials on the quality of life in patients with newly diagnosed urinary cancer before surgery. Methods Patients with urinary cancer were retrospectively enrolled from April 2020 to March 2021.
Yajian Li, Guanghua Huang, Wenjuan Cheng, Jiajie Wen, Xueer Chen, Yanhua Du, Hongzhe Shi   +6 more
wiley   +1 more source

Profile of European radiotherapy departments contributing to the EORTC Radiation Oncology Group (ROG) in the 21st century

, 2008
Since 1982, the Radiation Oncology Group of the EORTC (EORTC ROG) has pursued an extensive Quality Assurance (QA) program involving all centres actively participating in its clinical research.
Collette, L., Budiharto, Tom, Hurkmans, Coen, Aird, Edwin, Musat, Elena, Duclos, F., Davis, Bernard, Poortmans, P., Aird, E., Monti, A., Monti, Angelo, Musat, E., Collette, Laurence, Bar-Deroma, R., Davis, B., Bernstein, Zvi, van Tienhoven, Geertjan, Poortmans, Philip, Tienhoven, G., Hurkmans, C., Bar-Deroma, Raquel, Duclos, Frédéric, Bernstein, Z., Budiharto, T.   +23 more
core   +1 more source

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

VIEW, EarlyView.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao, Qiyu Huang, Juan Xiao, Ziyu Liu, Xinyan Zou, Yuying Liu, Lizhi Liu, Musheng Zeng, Chuanbo Xie   +8 more
wiley   +1 more source

Impact of pneumonitis from radiotherapy combined with immune checkpoint inhibitors therapy on tumor progression and survival in patients with non-small cell lung cancer

Frontiers in Immunology
PurposeThis study evaluates the impact of thoracic radiotherapy (TRT) combined with immune checkpoint inhibitors (ICIs) treatment-related pneumonitis on tumor progression and prognosis in patients with non-small cell lung cancer (NSCLC).MethodsData were ...
Ziwei Wang, Ziwei Wang, Kunpeng Xu, Han Sun, Jun Liang, Wei Jiang, Luhua Wang, Luhua Wang   +7 more
doaj   +1 more source

CT‐derived quantitative imaging metrics for pathological assessment of stage I pulmonary invasive adenocarcinoma: For the diagnostic examination, uAI Intelligent Imaging System was employed

VIEW, EarlyView.
This study explored uAI‐derived quantitative CT features for pathological grading of stage‐I invasive lung adenocarcinoma. Using 5‐fold cross‐validation, the Random Forest model achieved optimal discriminatory performance (mean AUC = 0.799). Attenuation and texture CT features enable non‐invasive grading and may assist clinical decision‐making ...
Qilong Wang, Wenjian Wang
wiley   +1 more source

Dose escalation in radical radio(chemo)therapy for cervical and upper thoracic esophageal cancer with 3DCRT/IMRT (ChC&UES): a multicenter retrospective study

Radiation Oncology
Background Cervical and upper thoracic esophageal cancer (ESCA) presents treatment challenges due to limited clinical evidence. This multi-center study (ChC&UES) explores radical radio(chemo)therapy efficacy and safety, especially focusing on radiation ...
Xiao-Han Zhao, Wen-Cheng Zhang, Xin Wang, Jun-Qiang Chen, Yuan-Ji Xu, Kuai-Le Zhao, Wei Huang, Pu-Dong Qian, Ya-Tian Liu, Xiao-Lin Ge, Xiao-Jie Xia, Chen-Gang Weng, Chun-Yue Gai, He-Song Wang, Hong-Mei Gao, Wen-Bin Shen, Shu-Chai Zhu   +16 more
doaj   +1 more source