Results 181 to 190 of about 90,511 (304)

PHGDH Orchestrates Cell Cycle Progression to Drive Cardiomyocyte Proliferation and Myocardial Regeneration via TGF‐β/Smad Signalling Pathway

open access: yesCell Proliferation, EarlyView.
PHGDH promoted cardiomyocyte proliferation and myocardial regeneration via cell cycle and TGF‐β/Smad signalling pathways during cardiac repair. Moreover, PHGDH benefits cardiac repair and cardiomyocyte proliferation in mammalian mice following MI. ABSTRACT The mature mammalian heart has limited ability for self‐repair and regeneration.
Han Zhang   +6 more
wiley   +1 more source

Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Hematologic malignancies represent the most common cancers in children. While the mainstays of treatment are chemotherapy and potentially hematopoietic stem cell transplant, minimally invasive surgery (MIS) has a role in the diagnosis and management of complications related both to disease and therapy as well as common pediatric surgical ...
Alejandro Chara   +3 more
wiley   +1 more source

Postoperative Care and Management in Pediatric Hematology‐Oncology Patients

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Pediatric patients with hematologic and oncologic diseases often undergo surgical procedures as part of diagnosis and therapy. These include central venous catheter placements, tumor resections, lymph node and bone marrow biopsies, among others.
Shachi Srivatsa, Sara A. Mansfield
wiley   +1 more source

3D virtual histology demonstrates tumour connectivity in spread through air spaces (STAS) of non‐small cell lung cancer

open access: yesHistopathology, EarlyView.
STAS‐positive lung nodules were analysed using histology, clinical CT, and synchrotron‐based μCT. μCT enables 3D spatial insights of STAS clusters which appear consistently connected to alveolar or vascular structures, suggesting non‐random distribution.
Giulia Saccomano   +7 more
wiley   +1 more source

High prevalence of loss of Claudin‐18 expression in invasive non‐mucinous lung adenocarcinoma: Potential diagnostic implications in routine practice

open access: yesHistopathology, EarlyView.
Loss of Claudin‐18 (Cldn18) expression is a frequent and specific feature of non‐mucinous lung adenocarcinoma (NM‐LUAD). Cldn18 immunohistochemistry may serve as an ancillary tool for distinguishing malignant from non‐neoplastic alveolar epithelium, as well as for differentiating NM‐LUADs with mucin production from M‐LUADs, particularly in small or ...
Stefano Lucà   +18 more
wiley   +1 more source

Who can safely discontinue lifelong follow‐up among patients with sporadic pheochromocytoma and paraganglioma?

open access: yesJournal of Internal Medicine, EarlyView.
Background Current guidelines recommend at least 10 years of follow‐up for all pheochromocytoma and paraganglioma (PPGL) patients and lifelong monitoring for high‐risk individuals. Nonetheless, data identifying patients who may not require routine lifelong follow‐up are scarce.
Min Jeong Park   +15 more
wiley   +1 more source

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