Results 161 to 170 of about 520,129 (244)

Poorly differentiated lung adenocarcinomas with concurrent ALK and CD30 expression: a diagnostic pitfall mimicking ALK‐positive anaplastic large‐cell lymphoma

Histopathology, EarlyView.
Poorly differentiated lung adenocarcinomas with concurrent anaplastic lymphoma kinase (ALK) and CD30 expression closely mimic ALK‐positive anaplastic large‐cell lymphoma, creating a significant diagnostic pitfall. Accurate classification requires comprehensive integration of clinical, radiologic, morphologic, immunophenotypic and molecular findings ...
Jietian Jin, Wenjian Cen, Qin Yan, Yangshan Chen, Chaoyun Huang, Yanfeng Feng, Neng Jiang   +6 more
wiley   +1 more source

Intratumoral IDH1 mutation status in intrahepatic cholangiocarcinoma is homogeneous

Histopathology, EarlyView.
IDH1 mutations are spatially homogeneous in intrahepatic cholangiocarcinoma. Single‐sample molecular testing is sufficient for clinical decision‐making. Introduction IDH1 mutations occur in approximately 10%–20% of intrahepatic cholangiocarcinoma (iCCA) and constitute an established target for molecularly guided therapy.
Sharon Weidmann, Silvana Ebner, Aayushi Srivastava, Armin Wiegering, Stefan Zeuzem, Peter J. Wild, Maximilian N. Kinzler, Melanie C. Winter, Dirk Walter   +8 more
wiley   +1 more source

Clinical outcomes of thoracic radiotherapy in combination with chemoimmunotherapy in elderly patients with extensive-stage small cell lung cancer. [PDF]

Precis Radiat Oncol
Han J, Zheng W, Jiang J, Shi H, Liu C.
europepmc   +1 more source

Low frequency of MTAP co‐deletion with CDKN2A in peritoneal mesothelioma suggests an independent diagnostic role for MTAP

Histopathology, EarlyView.
Aims Loss of MTAP expression by immunohistochemistry (IHC) is widely used as a surrogate for CDKN2A homozygous deletion (HD) in pleural mesothelioma (PM), but its diagnostic value in peritoneal mesothelioma (PeM) is less well defined. We investigated whether the observed limited reliability of MTAP IHC in PeM reflects a lower frequency of MTAP/CDKN2A ...
Andrea Quaranta, Donato Mancini, Concetta Caporusso, Andrea Marzullo, Luigi Vimercati, Cecilia Salzillo, Federica Pezzuto, Fiorella Calabrese, Gabriella Serio   +8 more
wiley   +1 more source

Improving timeliness of lung cancer care through a rapid assessment clinic

Internal Medicine Journal, EarlyView.
Abstract Background Early diagnosis and treatment of lung cancer improve survival. Guidelines from Australia and worldwide stipulate timeframes of care from referral. The Rapid Lung Assessment Clinic (RLAC) was established to fast‐track the diagnostic and treatment pathway, with a subsequent quality improvement initiative based on the initial analysis ...
Shakti V. Dabholkar, Shalini Vinod, Zinta Harrington, Benjamin Kolevski, Beth Ivimey, Joseph Descallar, Jonathan P. Williamson   +6 more
wiley   +1 more source

Consolidative thoracic radiotherapy after first-line chemoimmunotherapy in extensive-stage small-cell lung cancer: a multicenter retrospective study. [PDF]

Transl Lung Cancer Res
Zhang S, Lin N, Gu X, Cheng Z, Lin X, Liang X, Yang X, Chen J, Ma X, Liao H.   +9 more
europepmc   +1 more source

Frailty and Five‐Year Mortality After TAVR in Patients Aged 75 Years and Older

Journal of the American Geriatrics Society, EarlyView.
In patients aged 75 years and older undergoing transcatheter aortic valve replacement, frailty assessed by the Clinical Frailty Scale was the most robust geriatric factor independently associated with five‐year mortality. This study highlights the specific prognostic value of frailty beyond short‐term outcomes.
Jérémie Huet, Mélissa Sabin, Thierry Le Tourneau, Thibaut Manigold, Anne‐Sophie Boureau   +4 more
wiley   +1 more source

An LDH-based prognostic model for extensive-stage small-cell lung cancer patients treated with chemo-immunotherapy and consolidative thoracic radiotherapy. [PDF]

Front Endocrinol (Lausanne)
Zhao Y, Zou Y, Zhang S, Zhang Y, Zhou X, Li S, Zhou Y.   +6 more
europepmc   +1 more source

Survival outcomes in dogs treated with vinorelbine‐based adjuvant treatment following surgical resection of grade II and III pulmonary carcinoma

Journal of Small Animal Practice, EarlyView.
Objectives Pulmonary carcinoma in dogs is commonly managed with surgical resection; however, the role of adjuvant chemotherapy for grade II and III carcinomas remains unclear. This retrospective multicentre study investigated the outcomes in dogs treated with vinorelbine‐based adjuvant treatment (as monotherapy or combined chemotherapy) following ...
N. Wong, L. Brockley, S. Rajan, J. Yu
wiley   +1 more source

Thoracic radiotherapy may enhance the survival of patients with low-risk advanced lung adenocarcinoma based on protein biomarkers. [PDF]

Precis Radiat Oncol
Meng C, Wang F, Wang J, Tian J, Li X, Lu H, Zhao L, Wang P.   +7 more
europepmc   +1 more source