Results 151 to 160 of about 520,129 (244)

Consolidative thoracic radiotherapy following first-line chemo-immunotherapy in extensive-stage small-cell lung cancer: A systematic review and meta-analysis. [PDF]

Ther Adv Med Oncol
Canaslan K, Kahraman EG, Öztop İ, Güven DC.   +3 more
europepmc   +1 more source

Human Pancreatic Cancer Organoids

Cell Proliferation, EarlyView.
This guideline establishes a comprehensive framework for the application of patient‐derived pancreatic cancer organoids. It outlines the stringent technical requirements and testing methods necessary to ensure high fidelity to the original tumor tissue, including morphological assessment, pathological biomarker expression (e.g., CK19, CK7), and genetic
Aina He, Xiaolin Lin, Xiaozhe Qian, Jiasheng Mu, Zhonghua Tao, Jin Gu, Yonggang Wang, Ting Han, Hongling Zhao, Yalong Wang, Jian Zhang, Zunqiang Zhou, Ligang Xing, Changchun Zhou, Dongyuan Zhu, Zengjun Liu, Gang Chen, Qinghe Zhou, Xiaoguang Wang, Shasha Zhao, Xiao Liu, Dongyan Cao, Bin Yu, Zebing Liu, Jiabei Wang, Gengming Niu, Guiying Wei, Maorong Chen, Weiping Wang, Xiaonan Kang, Junmei Zhou, Shuai Gong, Ying Xie, Jianming Zhang, Xianming Kong, Chunyan Dong, Yanmei Zou, Lina Tang, Aijin Ma, Hua Xiong, Xuemei Liu, Tongbiao Zhao, Jie Hao, Xiuying Xiao, Dongxi Xiang   +44 more
wiley   +1 more source

A prospective multicenter trial of deep learning auto-segmentation for organs at risk in thoracic radiotherapy. [PDF]

Nat Commun
Niu G, Guan Y, Zhang Y, Song Y, Yan M, Li S, Liu T, Huang S, Chen J, Wang X, Zhang W, Meng M, Liu Y, Chen J, Fu Y, Zhao D, Huang J, Yang K, Cao J, Yuan H, Guo S, Pei X, Wu D, Nan Y, Yan Z, Lu Y, Zhao L, Yuan Z.   +27 more
europepmc   +1 more source

Decoverslipping of Archival Cytology Aspirate Smears for Ancillary Studies: A Review of Methods and Institutional Experience With Freezer‐Based Techniques

Cytopathology, EarlyView.
Freezer‐based decoverslipping of archival cytology aspirate smears achieved only 32.5% slide‐level success (26/80), with mounting medium composition and coverslip material, not freezing temperature or duration, identified as dominant determinants, underscoring the need to align coverslipping practices with anticipated ancillary testing requirements ...
Nyein Nyein Htun, Sinchita Roy‐Chowdhuri, Benjamin B. Morris, Gloria Hopkins Sura   +3 more
wiley   +1 more source

Adapting federated radiomics models for radiation pneumonitis prediction in patients receiving thoracic radiotherapy with immunotherapy. [PDF]

Front Immunol
Zhu Z, Yan M, Ji W, Zhang Z, Dekker A, Wee L, Zhang T, Lai X.   +7 more
europepmc   +1 more source

Evaluating Fine Needle Aspiration Cytology for Diagnostics of Soft Tissue and Bone Tumours

Cytopathology, EarlyView.
Systematic comparison of needle aspiration cytology and histopathology for 503 tumours in soft tissue and bone showed high concordance (positive predictive value 94%–100%, negative predictive value 83%–89%). In this original study, the authors show that FNAC is a safe and non‐invasive method for diagnosing suspected sarcomas, with the main objective to
Amanda Husu, Sandra Wessman, Karin Wallander, Felix Haglund de Flon   +3 more
wiley   +1 more source

NFE2L2‐mutated urothelial carcinomas frequently show concomitant myxoid and squamous features and have high PD‐L1 expression

Histopathology, EarlyView.
Aims NFE2L2 encodes the transcription factor, NRF2, which is a regulator of cellular oxidative stress responses and metabolic homeostasis. NFE2L2 alterations are implicated in multiple cancers, with significant study in thoracic oncology, with an adverse prognosis, aggressive behaviour, metabolic reprogramming and diminished responses to chemotherapy ...
Dane Wuori, Alexander Guzzetta, Melissa Y. Tjota, Peng Wang, Tatjana Antic, Jung Woo Kwon   +5 more
wiley   +1 more source

No detectable early subclinical cardiotoxicity within 12 weeks of thoracic radiotherapy under predominantly low cardiac dose exposure: a prospective cohort study. [PDF]

Cardiooncology
Valdés-Orrego I, Acevedo F, Merino T.
europepmc   +1 more source

HMGA2 is a highly sensitive marker for DICER1‐related tumours

Histopathology, EarlyView.
Aims DICER1 is a microRNA biogenesis enzyme that, when mutated, results in a rewiring of the transcriptome. Germline pathogenic variants (PVs) in DICER1 result in DICER1‐related tumour predisposition (DRTP) characterized by 30 or more different, generally rare, paediatric or adolescent‐onset tumours.
Paul S. Thorner, Anne‐Laure Chong, Naciba Benlimane, Lili Fu, Marc R. Fabian, William D. Foulkes   +5 more
wiley   +1 more source

Role of thoracic radiotherapy for extensive-stage small cell lung cancer in the era of immunotherapy: a review of current evidence. [PDF]

Front Immunol
Li Z, Lei X, Guo X, He Q, Han Y, Zhang P, Du L, Qu B.   +7 more
europepmc   +1 more source