Results 111 to 120 of about 355,737 (266)

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

open access: yesAdvanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao   +12 more
wiley   +1 more source

A case of aortic surgery-related chylothorax treated successfully by thoracoscopic ligation of the thoracic duct

open access: bronze, 2010
Hirohisa Kato   +5 more
openalex   +2 more sources

Thoracic Epidural versus  Intravenous Patient-controlled Analgesia after Cardiac Surgery [PDF]

open access: bronze, 2005
Vigdis Hansdottir   +5 more
openalex   +1 more source

Minimally Invasive Esophagectomy for Esophageal Cancer: Current Evidence and Future Perspectives

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Esophageal cancer is a highly aggressive malignancy with regional variations in histological subtypes. Adenocarcinoma predominates in Western countries, whereas squamous cell carcinoma is more common in Asia. Despite advances in multimodal therapy, esophagectomy remains the cornerstone of curative treatment, and the development of various ...
Hirotaka Konishi   +3 more
wiley   +1 more source

Clinical and Surgical Perspectives on Isolated Thoracic Ectopia Cordis: A Rare Case Report

open access: yesCase Reports in Pediatrics
Ectopia cordis is an exceptionally uncommon congenital condition where the heart develops outside its normal position due to incomplete closure of the ventral chest wall during embryogenesis.
Syed Mohsin Raza Bukhari   +8 more
doaj   +1 more source

Aprotinin use in thoracic aortic surgery: Safety and outcomes [PDF]

open access: bronze, 2006
Artyom Sedrakyan   +5 more
openalex   +1 more source

Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This review critically reassesses our prior hypothesis and proposes a revised anatomical model of the fusion fascia that is broadly applicable to GI cancer surgeries grounded in the principles of mesenteric resection. Our synthesis suggests that the fusion fascia is neither a dense connective tissue membrane nor a remnant of mesothelial fusion, but ...
Hisashi Shinohara   +9 more
wiley   +1 more source

Exercise and Nutrition Prehabilitation Program During Preoperative Chemotherapy Followed by Esophagectomy in Older Patients With Esophageal Cancer: A Randomized Clinical Trial

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This prospective randomized trial evaluated whether prehabilitation, exercise and nutrition intervention, enhance skeletal muscle mass during neoadjuvant chemotherapy in older patients with esophageal cancer undergoing esophagectomy. We also investigated whether exercise alone was sufficient to increase skeletal muscle mass, and whether nutritional ...
Keijiro Sugimura   +7 more
wiley   +1 more source

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