Results 111 to 120 of about 3,114,604 (362)
Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway
Advanced Science, EarlyView.A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang +8 morewiley +1 more source2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association of Cardio-Thoracic Surgery (EACTS).
European Heart Journal, 2020 G. Hindricks, Tatjana Potpara, Nikolaos Dagres, Elena Arbelo, Jeroen J. Bax, Carina Blomström-Lundqvist, G. Boriani, Manuel Castellá, Gheorghe-Andrei Dan, Polychronis E. Dilaveris, Laurent Fauchier, G. Filippatos, Jonathan M Kalman, M. la Meir, Deirdre A. Lane, Jean-Pierre Lebeau, M. Lettino, G. Lip, Fausto J. Pinto, G. Thomas, M. Valgimigli, I. V. van Gelder, Bart Van Putte, Caroline L Watkins, P. Kirchhof, Michael Kühne, V. Aboyans, Anders Ahlsson, P. Balsam, Johann Bauersachs, S. Benussi, Axel Brandes, Frieder Braunschweig, A. Camm, Davide Capodanno, Barbara Casadei, D. Conen, H. Crijns, Victoria Delgado, Dobromir Dobrev, Heinz Drexel, Lars Eckardt, Donna Fitzsimons, Thierry Folliguet, Chris P. Gale, B. Gorenek, K. Haeusler, Hein Heidbuchel, Bernard Iung, Hugo A. Katus, D. Kotecha, Ulf Landmesser, Christophe Leclercq, Basil S. Lewis, J. Mascherbauer, J. L. Merino, Béla Merkely, Lluís Mont, Christian Mueller, K. V. Nagy, Jonas Oldgren, Nikola Pavlović, Roberto F E Pedretti, Steffen Petersen, J. Piccini, Bogdan A Popescu, H. Pürerfellner, Dimitrios J. Richter, M. Roffi, A. Rubboli, D. Scherr, Renate B. Schnabel, Iain A Simpson, E. Shlyakhto, Moritz F. Sinner, J. Steffel, M. Sousa‐Uva, P. Suwalski, M. Svetlosak, R. Touyz, Stephan Windecker, C. Baigent, Jean-Philippe Collet, V. Dean, D. Grobbee, Sigrun Halvorsen, P. Jüni, A. Sonia Petronio, T. Delassi, H. Sisakian, Alexandr Chasnoits, M. De Pauw, Elnur Smajić, T. Shalganov, P. Avraamides, Josef Kautzner, Christian Gerdes, Ahmad Abd Alaziz, P. Kampus, P. Raatikainen, S. Boveda, G. Papiashvili, Vassilios Vassilikos, Zoltán Csanádi, D. Arnar, Joseph Galvin, A. Barsheshet, P. Caldarola, A. Rakisheva, I. Bytyçi, Alina Kerimkulova, O. Kalējs, Mario Njeim, A. Puodziukynas, L. Groben, M. A. Sammut, A. Grosu, A. Bošković, A. Moustaghfir, N. D. de Groot, Lidija Poposka, O. Anfinsen, Przemysław Mitkowski, Diogo Cavaco, C. Silişte, Evgeny N Mikhaylov, Luca Bertelli, D. Kojic, Róbert Hatala, Z. Fras, Fernando Arribas, T. Juhlin, C. Sticherling, Leila Abid, I. Atar, O. Sychov, Matthew G. D. Bates, Nodir U Zakirov +137 moresemanticscholar +1 more sourceInactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension
Advanced Science, EarlyView.Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang +17 morewiley +1 more sourceDCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex
Advanced Science, EarlyView.This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.Zhenyi Wang, Huanhuan Huang, Kaizong Huang, Xiaowen Cui, Leilei Wu, Renyu Lin, Zhe Zhao, Hua Chen, Cheng Zheng, Weilin Jin, Song Chen, Jiayan Chen, Yaping Xu, Dongping Wei +13 morewiley +1 more sourceTHORACIC SURGERY IN EQUINES
The Iraqi Journal of Veterinary Medicine, 1987
Unilateral. thoracotomy was performed in twenty nine donkeys and twenty five horses aged 4-10 years without an ‘aid of positive ‘respirator. Surgical pneumothorax did not endanger the life of patient.N. M. Jawaddoaj +1 more source
