Results 101 to 110 of about 1,954,486 (311)

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

Advanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo, Cui Yang, Liuzhou Mao, Panqin Ma, Chiyu Jia, Karen Yuanting Tang, Xian Jun Loh, Yun‐Long Wu   +7 more
wiley   +1 more source

Selective lobar collapse for video-assisted thoracic surgery

, 2004
Background. Video-assisted thoracic surgery (VATS) is conventionally performed under single-lung ventilation. A small proportion of patients are often excluded from undergoing VATS because of their inability to tolerate single-lung ventilation.
Ho, KM, Yim, APC, Lee, TW, Sihoe, ADL, Sze, TS   +4 more
core   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

Awake thoracic surgery: a historical perspective

, 2012
During the early twentieth century, thoracic surgery procedures were frequently attempted through local anesthesia, although the pneumothorax created after opening of the chest wall was deemed invariably fatal.
MINEO, TOMMASO CLAUDIO, Mineo, TC, Pompeo, E, POMPEO, EUGENIO   +3 more
core   +1 more source

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

Advanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng, Xiaomiao Chai, Peng Jin, Xin Xin, Yingjie Li, Chun Yang, Jia Wei, Zishuo Yan, Jingyu Zhang, Qianning Zhao, Yingchen Han, Ning Zhang, Fuze Li, Bo Qiao, Huan Wang, Huachuan Zheng, Yan Li, Xin Zhang, Yan Zhao, Wenjun Mao, Jing Zhang   +20 more
wiley   +1 more source

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

Advanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu, Ming Zhang, Yunxiang Feng, Yibo Deng, Kai Zhao, Xiangyu Li, Yun Lu, Li Tian, Tao Yang, Wei Yao, Jianming Wang, Zhengdong Deng   +11 more
wiley   +1 more source

Cirurgia torácica geral em pacientes com revascularização miocárdica prévia Non-cardiac thoracic surgery in patients with previous myocardial revascularization

Brazilian Journal of Cardiovascular Surgery, 1995
É analisada a experiência da Disciplina de Cirurgia Torácica da Faculdade de Medicina da Universidade de São Paulo, em 24 pacientes submetidos a cirurgia torácica com revascularização miocárdica prévia.
Paulo M Pêgo-Fernandes, Fábio B Jatene, Alexandre Wada, André Toraso Yamazaki, Erika Miyoshi, Mário Terra Filho, Adib D Jatene   +6 more
doaj  

Safe implementation of robot-assisted thoracic surgery in the UK: a single-centre experience and early outcomes

Journal of Cardiothoracic Surgery
Background Robot-assisted thoracic surgery (RATS) is a recognised alternative to video-assisted thoracic surgery (VATS) but remains under utilised in the UK. We describe the establishment of a RATS lobectomy service, outlining peri-operative outcomes and
Michelle Lee, Ee Phui Kew, Mark Edsell, Jeremy Smelt   +3 more
doaj   +1 more source

Videotoracoscopia no trauma de tórax

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVOS: Com o intuito de definir a função da videotoracoscopia no diagnóstico e tratamento no trauma torácico, foram estudados 51 traumatizados por traumas penetrantes ocasionados por arma branca, ferimentos por projétil de arma de fogo ou traumas ...
Vicente Dorgan Neto, Roberto Saad Júnior, Samir Rasslan   +2 more
doaj   +1 more source

Diagnostic Video-Assisted Thoracic Surgery

, 1996
All patients who underwent video-assisted thoracic surgery (VATS) for diagnostic purposes from Jan. 1992 to Aug. 1995 were reviewed. The total number of patients were 111 with 57 male and 54 female, and the mean age was 49 years (range 1 to 74). Multiple
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