Results 111 to 120 of about 1,954,486 (311)

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu   +10 more
wiley   +1 more source

Robotic thoracic surgery: The state of the art

open access: yesJournal of Minimal Access Surgery, 2015
Minimally invasive thoracic surgery has come a long way. It has rapidly progressed to complex procedures such as lobectomy, pneumonectomy, esophagectomy, and resection of mediastinal tumors.
Arvind Kumar, Belal Bin Asaf
doaj   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

open access: yesAdvanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li   +15 more
wiley   +1 more source

THORACIC ENDOMETRIOSIS — THE RARE PATHOLOGY IN THORACIC SURGERY

open access: yesВестник хирургии имени И.И. Грекова, 2018
Thoracic hematogenic endometriosis is a rare pathology. A clinical course hasn’t pathognomic symptoms, because of it, the diagnosis is established due to histological study.
A. A. Pichurov   +9 more
doaj   +1 more source

Short term prospective evaluation of microalbuminuria after thoracic surgery

open access: yes, 2011
OBJECTIVE Micro-albuminuria (MA) is associated with a generalized increase in systemic vascular permeability and a sensitive marker of endothelial dysfunction.
PUMA, Francesco   +7 more
core  

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

open access: yesAdvanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian   +12 more
wiley   +1 more source

A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance

open access: yesAdvanced Science, EarlyView.
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng   +12 more
wiley   +1 more source

Quiz: Thoracic Surgery

open access: yesHeart Vessels and Transplantation, 2022
Federico Tacconi
doaj   +1 more source

Enigmatic Contralateral Hemothorax after Left Thoracotomy

open access: yes, 2009
Intrathoracic hemorrhage following surgical intervention that needs rethoracotomy has a low rate in the daily practice of thoracic surgery. Hemothorax in the contralateral site is definitely unexpected after thoracotomy.
Gurses, Atilla   +5 more
core  

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