Results 121 to 130 of about 135,518 (301)
Background Lung cancer continues to be the primary cause of cancer-related deaths worldwide, with surgical resection recognised as the gold standard for non-small cell lung cancer. Recent innovations in thoracic surgery, including video-assisted thoracic
Michael Joseph Otorkpa +4 more
doaj +1 more source
Introduction Critical care, emergency medicine, and surgical trainees frequently perform surgical and Seldinger-technique tube thoracostomy, thoracentesis, and thoracic ultrasound.
Jacob LoMonaco +6 more
doaj +1 more source
Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan +10 more
wiley +1 more source
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo +7 more
wiley +1 more source
Hybrid Approach of Aortic Diseases: Zone 1 Delivery and Volumetric Analysis on the Descending Aorta
Introduction: Conventional techniques of surgical correction of arch and descending aortic diseases remains as high-risk procedures. Endovascular treatments of abdominal and descending thoracic aorta have lower surgical risk. Evolution of both techniques
José Augusto Duncan +6 more
doaj +1 more source
Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li +11 more
wiley +1 more source
The short-term effects of coronary artery bypass graft (CABG) surgery on cognitive performance
Includes bibliographical references (leaves 63-74).Considerable research evidence suggests that post-operative cognitive impairment is a common complication of coronary artery bypass graft (CABG) surgery.
Chiang, Yin-Jung Helen
core
Biomarkers of Sarcopenia: Current Status and Future Perspectives
In this review, we summarize the various biomarkers discovered in recent years, including biochemical, imaging, and physical testing markers. We analyze their advantages and disadvantages and propose potential ways to improve the diagnostic accuracy of biomarkers, as well as future research directions.
Bijin Luo +6 more
wiley +1 more source
Objectives: The goal of this multicentre retrospective cohort study was to evaluate technical success and early and late outcomes of thoracic endovascular repair (TEVAR) with grafts deployed upside down through antegrade access, to treat thoracic aortic ...
Bonardelli, Stefano +10 more
core +1 more source

