Results 131 to 140 of about 97,665 (332)

Exercise‐induced effects on atherogenesis and tryptophan catabolism via the kynurenine pathway in an HIV‐associated atherosclerosis mouse model

open access: yesExperimental Physiology, EarlyView.
Abstract A mouse model of HIV‐associated atherosclerosis (Tg26+/−ApoE−/−) exhibited increased plaque area compared with the ApoE−/− mouse, linked to elevated indoleamine 2,3‐dioxygenase (IDO) activity. IDO catalyses the conversion of tryptophan (TRP) into kynurenine (KYN), measured by the KYN‐to‐TRP ratio.
Marcus V. S. Rangel   +5 more
wiley   +1 more source

Pericardial Pressure during Transverse Acceleration in Dogs without Thoracotomy [PDF]

open access: bronze, 1967
Natalio Banchero   +3 more
openalex   +1 more source

Effects of soluble guanylyl cyclase stimulation on muscle oxygenation and exercise capacity in heart failure with mildly reduced ejection fraction

open access: yesExperimental Physiology, EarlyView.
Abstract Heart failure (HF) with a mildly reduced ejection fraction (HFmrEF; 40%–49%) is present in ≤25% of HF patients. Therapeutic treatment options for HFmrEF‐associated exercise intolerance are limited. Nitric oxide (NO)‐independent stimulation of soluble guanylyl cyclase to improve peripheral vasodilatation offers a novel approach to enhance ...
Ramona E. Weber   +10 more
wiley   +1 more source

Impact of combined ginsenoside‐MC1 and irisin on mitochondrial apoptosis in diabetic rats with hepatic reperfusion injury: Role of AMPK/JNK signalling

open access: yesExperimental Physiology, EarlyView.
Abstract Hepatic ischaemia–reperfusion (IR) injury is a serious clinical issue, especially in patients with type 2 diabetes mellitus (T2DM). As mitochondria play a critical role in the regulation of IR‐induced liver damage, mitochondria‐targeted treatment is of the utmost significance for improving outcomes.
Jie Lin   +4 more
wiley   +1 more source

Ventilation-Perfusion Changes During Thoracotomy [PDF]

open access: bronze, 1966
robert virtue   +5 more
openalex   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

open access: yesExperimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer   +11 more
wiley   +1 more source

Ageing‐induced weakness of mouse NMJs is associated with reduced active zone density, synaptic event kinetics and presynaptic calcium entry

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A summary of age‐related changes contributing to reduced neurotransmission in mouse neuromuscular junctions (NMJ). At 26 months, NMJs showed potentiation in short‐term plasticity compared to 4‐ or 30‐month‐old synapses, which is a proxy for reduced probability of release within individual AZs (dashed arrow). Compared to NMJs from
Yizhi Li   +7 more
wiley   +1 more source

Video‐Assisted Thoracoscopic Removal of a Mediastinal Mass in a Newborn: A Case Report

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Carlo Maria Ferlini   +7 more
wiley   +1 more source

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