Results 91 to 100 of about 7,661,261 (288)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Future of Islamic Civilization, Emerging Issues and New Horizons
Journal of Islamic Thought and Civilization, 2019 This paper investigates four dimensions of Islamic Movements in Malaysian context. The first one is about the impacts of Islamic Movements instigating the development of Islamic civilization in Malaysia.
Sajid Iqbal Sheikh +1 more
doaj
Reflections on morality in Renaissance thought [PDF]
, 2015 We can read about the morality of that time in works by authors who describe or criticize the conduct and activity of the members of those classes taking the lead in the morality of that time.
Gluchman, Vasil
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Systemic and Anthropological Characteristics of Thinking
СибСкриптThe article describes such systemic anthropological characteristics of thinking as multidimensionality, projectivity, inclusion in life relationships, transtemporality, and nonlinearity.
Nikolay I. Nelyubin
doaj +1 more source
Metaphilosophy, 2005 This paper seeks to explain how thought experiments work, and also the reasons why they can fail. The paper is split into four sections. The first argues that thought experiments in philosophy and science should be treated together. The second examines existing accounts of thought experiments, and shows why they are inadequate.
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Studia Semiotyczne, 2021 DOI: https://doi.org/10.26333/sts.xxxv1.05 The format of mental representation is the way information is organized in the mind. The discussion surrounding the format of representation addresses the problem of what representational primitives are and ...
Piotr Kozak
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source