Results 71 to 80 of about 2,866,898 (311)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Thoughts about thoughts

open access: yesIzvestiya VUZ. Applied Nonlinear Dynamics, 1994
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openaire   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Contending Visions of Contemporary Islamic Reassertion

open access: yesJournal of Islamic Thought and Civilization, 2018
The understanding of contemporary Islamic activism has become one of the most important challenges for international academia since the 1980s. Late 1970s and early 1980s, witnessed a chain of unexpected but significant happenings in the heart of the ...
Mian Muhammad Rafi, Humaira Ahmad
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Selective scepticism over thought: am I ever justified in doubting that I think that thought but not this one?

open access: yes, 2016
In this paper, I subject a number of statements avowing selective doubt about an act of thinking to philosophical analysis (e.g., "A thought occurred just now but I do not believe that I was thinking it") to ascertain those circumstances under which they
Young, G, Garry Young
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A history of Australasian economic thought

open access: yes, 2017
This overview of Australasian economic thought presents the first analysis of the Australian economic contribution for 25 years, and is the first to offer a panoramic sweeping account of New Zealand economic thought.
Millmow, Alex, Alex Millmow
core   +1 more source

MYTHOLOGIC AND DESTRUCTION OF THE SCIENTIFIC AND ARCHAIC CONSCIOUSNESS (TRAVELING TO SOURCES OF PRESOCRATIC THINKING)

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2016
Purpose. The purpose of research consists in that: having plunged into depths of primitive consciousness (using the recipe of many thinkers of non-classical philosophy), to reveal contradiction of the European thought (at its sources) in Ancient Greek ...
V. B. Okorokov
doaj   +1 more source

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