Results 51 to 60 of about 2,866,898 (311)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

David Hume Düşüncesinde Duygu-Düşünce İlişkisinin İnsan Doğasında Temellendirilmesi

open access: yesTetkik, 2022
17. yüzyıl pek çok alanda olduğu gibi bilim ve felsefe açısından da önemli değişim ve dönüşümlere sebep olmuştur. Bu bağlamda Orta çağ düşüncesindeki Tanrı merkezli hâkim anlayışın yerini insan ve insan doğası bilimi almıştır.
Emrullah Kılıç
doaj   +1 more source

Thought, thoughts, and deflationism [PDF]

open access: yesPhilosophical Studies, 2016
Deflationists about truth embrace the positive thesis that the notion of truth is useful as a logical device, for such purposes as blanket endorsement, and the negative thesis that the notion doesn’t have any legitimate applications beyond its logical uses, so it cannot play a significant theoretical role in scientific inquiry or causal explanation ...
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Economic Thought in Eighteenth CenturyAmerica Prior to Indepencence

open access: yes, 2015
. This paper examines the state of economic thought in the United States during the time period 1700 to 1775, an era that marks the end of the colonial age for the new nation.
CICARELLI, James S.; roosevelt university
core   +1 more source

Institute for American Thought

open access: yes, 2013
poster abstractThis poster will have images of recent volumes published by the critical editions being edited by the Institute for American Thought. Information will tell how long the critical editions have been in existence, how much funding has been ...
IUPUI (Campus). Institute for American Thought
core   +1 more source

معاصر سماجی روئیے اور فرقہ واریت: بابا گرو نانک کی تعلیمات کی روشنی میں تنقیدی جائزہ

open access: yesPakistan Journal of Islamic Research, 2023
Baba Guru Nanak is a renowned social reformist, founder of Sikhism, a great poet, and philosopher of 21st century. His teachings carried the message of universal brotherhood and social revolution.
Faiza Malik, Tahira Basharat
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Thought Experiments in Current Metaphilosophical Debates

open access: yes, 2017
Thought experiments in philosophy and science have a lot in common. However, this chapter focuses on thought experiments in philosophy only. It provides an overview of the results that discussion has achieved and point out which issues are still open. In
Daniel Cohnitz   +3 more
core   +1 more source

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