Results 61 to 70 of about 2,120,226 (267)

MYTHOLOGIC AND DESTRUCTION OF THE SCIENTIFIC AND ARCHAIC CONSCIOUSNESS (TRAVELING TO SOURCES OF PRESOCRATIC THINKING)

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2016
Purpose. The purpose of research consists in that: having plunged into depths of primitive consciousness (using the recipe of many thinkers of non-classical philosophy), to reveal contradiction of the European thought (at its sources) in Ancient Greek ...
V. B. Okorokov
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Heritage Education and Citizenship in Early Childhood and Primary Education Based on Controversy: Conceptions of Future Teachers

open access: yesSocial Sciences
This study is based on heritage education as the ideal framework for laying the foundations of a democratic, participatory citizenship that is committed to its community and to social and ecological justice from an early age.
Sergio Sampedro-Martín   +3 more
doaj   +1 more source

Fundemental Aesthetics in Heideggerian Philosophy and Daoism [PDF]

open access: yesMetaphysics, 2015
Daoist aesthetics is based on the creative power of Dao which has a pre-ontological origin. The original context of creativity which arises from Dao, forms the foundation of art in Daoist thought.
Morteza Goodarzi, Aliasghar Mosleh
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A thought on a thought

open access: yes, 2013
Dois músicos sociólogos se fizeram a seguinte pergunta: como quatro caras que nunca se encontraram e que não têm nenhuma música escrita, apertam as mãos, e começam a tocar de uma forma que parece que eles estão trabalhando juntos há anos? Faulkner e Becker decidiram responder a pergunta com pesquisa de campo.
Becker, Howard S., Falkner, Robert R.
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Contending Visions of Contemporary Islamic Reassertion

open access: yesJournal of Islamic Thought and Civilization, 2018
The understanding of contemporary Islamic activism has become one of the most important challenges for international academia since the 1980s. Late 1970s and early 1980s, witnessed a chain of unexpected but significant happenings in the heart of the ...
Mian Muhammad Rafi, Humaira Ahmad
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy