Results 61 to 70 of about 2,866,898 (311)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Inhibition of learning motivation by thought suppression
, 2022 Thought suppression is a cognitive activity that individuals intentionally suppress to think about a target. Many previous studies showed that the participants who intended to suppress a target thought about the target more frequently than the ...
ナベタ , トモヒロ +3 more
core
A history of Scottish economic thought
, 2006 Modern economics has, at its foundation, scholarly contributions from many prominent Scottish thinkers. This revealing work examines the roots of this great tradition, places in perspective a selection of authors, and assesses their contribution over ...
Dow, Alexander, Dow, Sheila C.
core +2 more sources
Laying Foundations for Islamic Teacher Education
Education SciencesIncreasingly, educators committed to the vision of Islamic schooling are expressing sentiments of moral dissonance. On the one hand, they choose Islamic schools because they aspire to affect hearts, nurture whole human beings, and grow spiritually while ...
Nadeem A. Memon +2 more
doaj +1 more source
AI Can Never Think: The Uniqueness of Human Thought
Studia Gilsoniana, 2020 As the saying goes, imitation is the most sincere form of flattery, yet very few assume imitation to be equivalence. An original masterpiece may be worth millions while a copy, no matter how exact the resemblance, would yield just a fraction of the price.
Jason Nehez
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Philosophical Origins of Seventeenth Century American Economic Thought
, 2016 . This paper examines the philosophical origins of seventeenth century American economic thinking, considering the contributions of both Puritan thought as derived from the abundant written legacy its followers left behind, and that of Quaker thought ...
CICARELLI, James S.; Roosevelt Univeristy Department of Economics Chicago, Illinois USA
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source