Results 101 to 110 of about 7,661,261 (288)
Doubt in digital education: Critical thinking in the age of Trump [PDF]
Digital Culture & Education, 2017 Based on a taxonomy that includes discourse and ideology as well as logic and truth, this article identifies doubt as the element most critical to critical thinking.
Robert Nelson
doaj
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
10. The Political Thought of Machiavelli
, 1958 The national state in Western Europe was a new institution, without precedent in the European World. Its rise and almost immediate conflict with the Church challenged political theorists to reexamine the assumptions of a universal church in a universal ...
Bloom, Robert L. +6 more
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Creating a Supportive Work Environment: A Cognitive Behavioral Approach for Nurse Leaders
Nursing ReportsPurpose: This article focuses on identifying cognitive behavioral (CB) techniques that can help nurse supervisors more effectively navigate interpersonal challenges, reduce workplace stress, improve team cohesion, and, ultimately, enhance overall ...
Nurit Zusman +3 more
doaj +1 more source
Research as a problem and as an attitude
Revista Ingenio, 2016 The idea of the university as a refuge where knowledge matures away from the concerns of everyday life and where people go to drink in the compound of wisdom has become anachronistic.
Alberto Martínez Boom
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Mental Ownership and Higher Order Thought [PDF]
, 2010 Mental ownership concerns who experiences a mental state. According to David Rosenthal (2005: 342), the proper way to characterize mental ownership is: ‘being conscious of a state as present is being conscious of it as ...
Lane, Timothy, Liang, Caleb
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source