Results 21 to 30 of about 285,969 (269)

Francisella tularensis subsp. holarctica wild-type is able to colonize natural aquatic ex vivo biofilms

Frontiers in Microbiology, 2023
Biofilms are a matrix-associated lifestyle of microbial communities, often enabling survivability and persistence of such bacteria. The objective of this study was to investigate the survival of the wild-type strain A-271 of Francisella tularensis subsp.
Christoph Schaudinn, Kerstin Rydzewski, Kerstin Rydzewski, Beate Meister, Roland Grunow, Klaus Heuner, Klaus Heuner   +6 more
doaj   +1 more source

Puumala and Tula Virus Differ in Replication Kinetics and Innate Immune Stimulation in Human Endothelial Cells and Macrophages

Viruses, 2019
Old world hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) upon zoonotic transmission to humans. In Europe, the Puumala virus (PUUV) is the main causative agent of HFRS.
Daniel Bourquain, Clemens Bodenstein, Stefanie Schürer, Lars Schaade   +3 more
doaj   +1 more source

Cold stress tolerance of the intertidal red alga Neoporphyra haitanensis

BMC Plant Biology, 2022
Background Red algae Porphyra sensu lato grow naturally in the unfavorable intertidal environment, in which they are exposed to substantial temperature fluctuations. The strategies of Porphyra to tolerate cold stress are poorly understood. Results Herein,
Shanshan Zhu, Denghui Gu, Caiping Lu, Caixia Zhang, Juanjuan Chen, Rui Yang, Qijun Luo, Tiegan Wang, Peng Zhang, Haimin Chen   +9 more
doaj   +1 more source

Global ubiquitination analysis reveals extensive modification and proteasomal degradation of cowpox virus proteins, but preservation of viral cores

Scientific Reports, 2018
The emergence of Variola virus-like viruses by natural evolution of zoonotic Orthopoxviruses, like Cowpox virus (CPXV), is a global health threat. The proteasome is essential for poxvirus replication, making the viral components interacting with the ...
Marica Grossegesse, Joerg Doellinger, Annemarie Fritsch, Michael Laue, Janett Piesker, Lars Schaade, Andreas Nitsche   +6 more
doaj   +1 more source

Sucrose addition directionally enhances bacterial community convergence and network stability of the shrimp culture system

npj Biofilms and Microbiomes, 2022
Sucrose is an effective carbon source for creating more reliable and environmentally friendly conditions for shrimp growth by regulating bacteria in biofloc-based culture systems.
Haipeng Guo, Pengsheng Dong, Fan Gao, Lei Huang, Sipeng Wang, Ruoyu Wang, Mengchen Yan, Demin Zhang   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Selective replication and vertical transmission of Ebola virus in experimentally infected Angolan free-tailed bats

Nature Communications
The natural reservoir of Ebola virus (EBOV), agent of a zoonosis burdening several African countries, remains unidentified, albeit evidence points towards bats.
S. A. Riesle-Sbarbaro, G. Wibbelt, A. Düx, V. Kouakou, M. Bokelmann, K. Hansen-Kant, N. Kirchoff, M. Laue, N. Kromarek, A. Lander, U. Vogel, A. Wahlbrink, D. M. Wozniak, D. P. Scott, J. B. Prescott, L. Schaade, E. Couacy-Hymann, A. Kurth   +17 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Myocarditis associated with COVID-19 vaccination

npj Vaccines
Following the start of the COVID-19 vaccination campaign, the adverse events of myocarditis and pericarditis were linked mainly to mRNA COVID-19 vaccines by the regulatory authorities worldwide. COVID-19 vaccines have been administered to several million
Alessandra Buoninfante, Arno Andeweg, Georgy Genov, Marco Cavaleri   +3 more
doaj   +1 more source