Results 31 to 40 of about 285,969 (269)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Metabolomics Analysis for Nitrite Degradation by the Metabolites of Limosilactobacillus fermentum RC4

open access: yesFoods, 2022
Nitrite (NIT), a commonly used food additive, especially in pickled and cured vegetables and meat products, might cause acute and chronic diseases. Fermentation with lactic acid bacteria (LAB) is an effective method for degrading NIT and improving the ...
Chaoran Xia   +6 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

vPro-MS enables identification of human-pathogenic viruses from patient samples by untargeted proteomics

open access: yesNature Communications
Viral infections are commonly diagnosed by the detection of viral genome fragments or proteins using targeted methods such as PCR and immunoassays.
Marica Grossegesse   +5 more
doaj   +1 more source

Visualization of SARS-CoV-2 particles in naso/oropharyngeal swabs by thin section electron microscopy

open access: yesVirology Journal, 2023
Background SARS-CoV-2 replicates efficiently in the upper airways of humans and produces high loads of virus RNA and, at least in the initial phase after infection, many infectious virus particles.
Michael Laue   +3 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao   +5 more
wiley   +1 more source

Co-option of a non-retroviral endogenous viral element in planthoppers

open access: yesNature Communications, 2023
Non-retroviral endogenous viral elements (nrEVEs) are widely dispersed throughout the genomes of eukaryotes. Although nrEVEs are known to be involved in host antiviral immunity, it remains an open question whether they can be domesticated as functional ...
Hai-Jian Huang   +18 more
doaj   +1 more source

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs   +15 more
wiley   +1 more source

Lassa virus circumvents macrophage and dendritic cell antiviral defences in its natural reservoir, the Natal multimammate mouse (Mastomys natalensis)

open access: yesnpj Viruses
Lassa virus (LASV) is a zoonotic arenavirus that causes severe hemorrhagic fever in humans but persists asymptomatically in its natural reservoir, the Natal multimammate mouse (Mastomys natalensis, NMM).
Nicolas Corrales   +8 more
doaj   +1 more source

Quantifying the econometric loss of a cyber-physical attack on a seaport

open access: yesFrontiers in Computer Science, 2023
Modern Cyber-Physical Systems (CPS) show increasing levels of automation, intelligence, and optimization capabilities. Both creators and adopters of these technologies emphasize the benefits: safety, cost-savings, and efficiencies.
Kimberly Tam   +4 more
doaj   +1 more source

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