Results 151 to 160 of about 2,521,807 (266)

TCMD: A High‐Throughput and Rapid Method for Screening Antimicrobial Ingredients from Renewable Bio‐Based Resources

open access: yesAdvanced Science, EarlyView.
This study develops a strategy to screen the active compounds from bio‐mixtures via combining transcriptomic profiling and molecular docking. The proposed method demonstrates 100% correction in three different biobased mixtures and is 3–20 times faster than traditional approaches.
Yongdong Xu   +8 more
wiley   +1 more source

Two‐Step Tandem Catalysis for High‐Efficiency Ammonia Synthesis Via Nitrate Reduction on Anion‐Intercalated CoNi LDH and Cu/Cu2O

open access: yesAdvanced Science, EarlyView.
By integrating Cu/Cu2O and CoNi LDH, tandem kinetic descriptors, including a volcano curve, are employed to predict rate constants, facilitating ideal kinetic matching for efficient ammonia synthesis. The highest ammonia yield (1.12 mmol cm−2 h−1) and Faraday efficiency (99.78%) are achieved by rate matching between Cu/Cu2O and MoO4‐CoNi LDH.
Changzheng Lin   +11 more
wiley   +1 more source

Implementing Multimodal Hardware Security with 2D α‐In2Se3 Ferroelectric Transistor

open access: yesAdvanced Science, EarlyView.
A multimodal secure transistor‐integrated in‐memory sensing and computing architecture is demonstrated by leveraging its electronic and optoelectronic synaptic behaviors. Key security primitives, such as anticounterfeiting, watermarking, logic locking, and camouflaging, are implemented within a compact single‐transistor structure, providing a scalable ...
Xinwei Zhang   +11 more
wiley   +1 more source

Amino Acid‐Sensing Neurons in the Anterior Piriform Cortex Control Brown Adipose Tissue Thermogenesis

open access: yesAdvanced Science, EarlyView.
This study identifies a class of amino acid‐sensing neurons, APCCRH neurons, which regulate BAT thermogenesis. Leucine deficiency alters intrinsic excitability through GCN2 signaling pathway, activating APCCRH neurons, which in turn regulate BAT thermogenesis via projections to the lateral hypothalamus.
Peixiang Luo   +15 more
wiley   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

open access: yesAdvanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai   +9 more
wiley   +1 more source

Classification of direct threats to the conservation of ecosystems and species 4.0. [PDF]

open access: yesConserv Biol
Salafsky N   +14 more
europepmc   +1 more source

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