From Ancient Techniques to Modern Solutions: In Situ Synthesis of C‐S‐H for Sandstone Conservation
Herein, this work presents a paleo‐inspired approach to synthesizing and optimizing C‐S‐H‐based grouting mortars for conserving the sandstone of Beishan Grottoes, Dazu Rock Carvings, China. By achieving an optimal recipe compatible with natural sandstone, this work demonstrates the pivotal role of hydrogen bonding in the adhesion between C‐S‐H mortars ...
Mengjun Jia+9 more
wiley +1 more source
Improving risk analysis of the environmental drivers of the spillover, emergence/re-emergence and spread of Crimean-Congo haemorrhagic fever virus, Marburg virus and Middle East respiratory syndrome coronavirus in the East Africa Region. [PDF]
Ajumobi O+6 more
europepmc +1 more source
SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong+9 more
wiley +1 more source
Finding the pulse of healthy native freshwater mussels (order Unionida): Insights from propagation biologists. [PDF]
Mueller ME, LePrevost CE, Cope WG.
europepmc +1 more source
Through an amorphization strategy, the electronic structure of single‐atom Co is effectively modulated from a low spin state (Co‐CCN) to a high spin state (Co‐ACN). The rearrangement of the electronic configuration optimizes the d‐band center resulting in the selectivity of 1O2 with almost 100%.
Juanjuan Qi+9 more
wiley +1 more source
Imprint of ancestral and modern threats in human mind - experience of fear, disgust, and anger. [PDF]
Landová E+6 more
europepmc +1 more source
High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics
The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high‐throughput synthetic set up opens the door to investigating thousands of sequences in an economic way and ultimately identifies potent antisense oligonucleotides while also giving room
Giorgia Danti+3 more
wiley +1 more source
Prehospital Antibiotic Administration for Suspected Open Fractures: Joint COT/OTA/ACEP/NAEMSP/NAEMT Position Statement. [PDF]
Johnson JP+7 more
europepmc +1 more source
High‐Throughput MicroED for Probing Ion Channel Dynamics
High‐throughput MicroED offers a new approach for visualizing ion channel dynamics. This approach reveals NaK’s sodium binding modes and NaK2CNG’s potassium‐induced selectivity filter dilation and gating. By capturing these distinct structures, this work challenges traditional models of ion channel permeation and selectivity. Abstract Ion channels play
Marc J Gallenito+4 more
wiley +1 more source