Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges
Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
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Generative AI and LLMs for Critical Infrastructure Protection: Evaluation Benchmarks, Agentic AI, Challenges, and Opportunities. [PDF]
Yigit Y+8 more
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Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou+3 more
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PROTAC Technology as a New Tool for Modern Pharmacotherapy. [PDF]
Kubryń N+4 more
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Saarvienin A—A Novel Glycopeptide with Potent Activity against Drug‐Resistant Bacteria
A structurally distinct glycopeptide, saarvienin A, represents a new family of glycopeptide antibiotics consisting of five sugar/aminosugar units connected to a halogenated peptide core. Saarvienin A overcomes vancomycin resistance and shows strong activity against drug‐resistant Gram‐positive bacteria, in particular, high‐priority pathogens such as ...
Amninder Kaur+7 more
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Sialyl glycosides containing 4‐N‐derivatized sialic acids synthesized by a highly efficient one‐pot two‐enzyme (OP2E) chemoenzymatic sialylation strategy have been shown to be versatile probes. They can resist sialidase cleavage, be selective substrates by influenza sialidases, or be nanomolar substrate analog‐based inhibitors and affinity ligands ...
Yue Yuan+6 more
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Intrusion detection system for V2X communication in VANET networks using machine learning-based cryptographic protocols. [PDF]
Venkatasamy TK+3 more
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The extent of physical and psychological workplace violence experienced by prehospital personnel in Denmark: a survey. [PDF]
Schøsler B, Bang FS, Mikkelsen S.
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Patient perspective on the climate health emergency. [PDF]
Joy A.
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Intelligent two-phase dual authentication framework for Internet of Medical Things. [PDF]
Asif M+6 more
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