Results 51 to 60 of about 3,991,559 (290)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Universality in the Three-Body Problem for 4He Atoms

open access: yes, 2003
The two-body scattering length a for 4He atoms is much larger than their effective range r_s. As a consequence, low-energy few-body observables have universal characteristics that are independent of the interaction potential.
A. Bulgac   +59 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Effect of variation of charge in the circular restricted three-body problem with variable masses

open access: yesJournal of Taibah University for Science, 2019
In the present paper, we are concerned by some investigation on circular restricted three-body problem (CR3BP), where we assume that the primaries have variable masses and variable charges. Among the principal tools used in the present study, we cite the
Abdullah Abduljabar Ansari   +3 more
doaj   +1 more source

Periodic Orbits of the Restricted Three-Body Problem Based on the Mass Distribution of Saturn’s Regular Moons

open access: yesUniverse, 2022
This paper uses the Kolmogorov–Smirnov test to perform a fitting analysis on the mass data of Saturn’s regular moons and found that the lognormal distribution is its best-fitting distribution with an extremely high p-value of 0.9889.
Huan Cheng, Fabao Gao
doaj   +1 more source

The Eckart frame Hamiltonians in the three-body problem

open access: yes, 2013
The Eckart frame is used to separate out the collective rotations in the quantum three-body problem. Explicit expressions for the corresponding rotational and vibro-rotational (i.e. Coriolis) Hamiltonians are derived.
Meremianin, A. V.
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Classical Coulomb three-body problem in collinear eZe configuration

open access: yes, 2003
Classical dynamics of two-electron atom and ions H$^{-}$, He, Li$^{+}$, Be$^{2+}$,... in collinear eZe configuration is investigated. It is revealed that the mass ratio $\xi$ between necleus and electron plays an important role for dynamical behaviour of
Einstein A   +15 more
core   +3 more sources

Black Hole Binary Formation in the Expanding Universe --- Three Body Problem Approximation --- [PDF]

open access: yes, 1998
We study black hole MACHO binary formation through three-body interactions in the early universe at $t\sim 10^{-5}$s. The probability distribution functions of the eccentricity and the semimajor axis of binaries as well as of the coalescence time are ...
B. D. Fields   +38 more
core   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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