Results 41 to 50 of about 3,476,424 (344)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Extended Class of Dubrovin's Equations Related to the One-Dimensional Quantum Three-Body Problem [PDF]

open access: yes, 1997
The relation of the quantum 1D three-body problems with zero-range interaction to the matrix Riemann-Hilbert problem with meromorphic coefficient is shown.
KUPERIN, Yu. A., DMITRIEVA, L. A.
core  

Three helium atoms and the scaling limit

open access: yes, 1999
We show that a scaling limit approach, previously applied in three-body low-energy nuclear physics, is realized for the first excited state of He-4 trimer.
Delfino, A.   +7 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

One-Dimensional Relativistic Self-Gravitating Systems

open access: yesEntropy
One of the oldest problems in physics is that of calculating the motion of N particles under a specified mutual force: the N-body problem. Much is known about this problem if the specified force is non-relativistic gravity, and considerable progress has ...
Robert B. Mann
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Efimov three-body states on top of a Fermi sea

open access: yesNew Journal of Physics, 2014
The stabilization of Cooper pairs of bound electrons in the background of a Fermi sea is the origin of superconductivity and the paradigmatic example of the striking influence of many-body physics on few-body properties.
Nicolai Gayle Nygaard   +1 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Bi-indicator driven surrogate-assisted multi-objective evolutionary algorithms for computationally expensive problems

open access: yesComplex & Intelligent Systems, 2023
This paper presents a bi-indicator-based surrogate-assisted evolutionary algorithm (BISAEA) for multi-objective optimization problems (MOPs) with computationally expensive objectives.
Wenxin Wang   +3 more
doaj   +1 more source

3D Human Motion Capture Method Based on Computer Vision

open access: yesAdvanced Engineering Research, 2023
Introduction. The analysis of approaches to tracking the human body identified problems when capturing movements in a three-dimensional coordinate system. The prospects of motion capture systems based on computer vision are noted.
A. D. Obukhov   +3 more
doaj   +1 more source

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