Results 81 to 90 of about 8,799,905 (264)

The nonlinear bending-torsion theory for curved rods as Gamma-limit of three-dimensional elasticity [PDF]

open access: yes, 2006
The problem of the rigorous derivation of one-dimensional models for nonlinearly elastic curved beams is studied in a variational setting. Considering different scalings of the three-dimensional energy and passing to the limit as the diameter of the beam
Scardia, L., Scardia, L Lucia
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Laminar flow in three-dimensional square-square expansions

open access: yes, 2011
In this work we investigate the three-dimensional laminar flow of Newtonian and viscoelastic fluids through square–square expansions. The experimental results obtained in this simple geometry provide useful data for benchmarking purposes in complex three-
Sousa, P.C.   +7 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

A scoping review on the potential of three-dimensional bioprinting in auricular cartilage regeneration

open access: yesSRM Journal of Research in Dental Sciences
Background The human ear significantly influences facial appearance. Auricular abnormalities can arise from many causes, and the cartilage cannot self-regenerate.
Eman Assem Ibrahim   +3 more
doaj   +1 more source

Three dimensional displays of tomographic images using shaded surfaces [PDF]

open access: yes, 1988
Several medical imaging techniques are capable of producing tomographic images, corresponding to cross-sections through the body. A stack of adjacent sections contains three dimensional information about the organs of interest, and this can be presented ...
Gibson, Christopher John
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

New three dimensional unilateral external fixator

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Many different external fixator desings have been developed. But most of the unilateral external fixator devices have unadequated for correction of the bone fragment positions and stabilization.
Hasan Havitcioglu   +4 more
doaj  

Three Dimensional Spheroid Co-culture Invasion Assay

open access: yesBio-Protocol, 2015
The assay was developed to investigate the impact of stromal cells of different types (in our case breast cancer associated fibroblasts stably manipulated to modify expression of genes of interest) on the invasive capacity of epithelial cancer cells (in ...
Eldo Verghese, Eldo Verghese
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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