Results 61 to 70 of about 1,393,595 (266)
Three Dimensional Spheroid Co-culture Invasion Assay
Bio-Protocol, 2015 The assay was developed to investigate the impact of stromal cells of different types (in our case breast cancer associated fibroblasts stably manipulated to modify expression of genes of interest) on the invasive capacity of epithelial cancer cells (in ...
Eldo Verghese, Eldo Verghese
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
New three dimensional unilateral external fixator
Acta Orthopaedica et Traumatologica Turcica, 2021 Many different external fixator desings have been developed. But most of the unilateral external fixator devices have unadequated for correction of the bone fragment positions and stabilization.
Hasan Havitcioglu +4 more
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Jitter Elimination in Shape Recovery by using Adaptive Neural Network Filter
Sensors, 2019 Three-dimensional (3D) cameras are expensive because they employ additional charged coupled device sensors and optical elements, e.g., lasers or complicated scanning mirror systems.
Sung-An Lee +2 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Biometrika, 1990 The biplot of a two-way table is discussed as a diagnostic tool for investigating bilinear models with additive terms for rows and columns and at least one multiplicative term. The full biplot is three dimensional with the points representing row effects concentrated is a plane orthogonal to another plane containing the points representing the column ...
openaire +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Three-Dimensional Analysis Of Influence Of Slow Maxillary Expansion
International Dental JournalAim or purpose: The purposes of this study were to evaluate the effect of slow maxillary expansion with a removable expansion appliance and analyze the changes in the three-dimensional space and eruption path of maxillary canines and premolars by a ...
Jin Hua Wang
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