Results 51 to 60 of about 1,308,969 (266)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Designing the image integrated between real reality and holography

Maǧallaẗ Al-Turāṯ wa Al-Taṣmīm
Three-dimensional holographic display technology is a sign of future technology and communications. This technology received global attention for the first time in 2008 when first time as a hologram with the aim of reducing the environmental impact of ...
Prof. Dr. Safwat Abdel Halim Prof. Dr. Wael Mohamed Anani Shehab Muhammad Jamal al-Din Qayati
doaj   +1 more source

Three dimensional canonical singularity and five dimensional N $$ \mathcal{N} $$ = 1 SCFT

Journal of High Energy Physics, 2017
We conjecture that every three dimensional canonical singularity defines a five dimensional N $$ \mathcal{N} $$ = 1 SCFT. Flavor symmetry can be found from singularity structure: non-abelian flavor symmetry is read from the singularity type over one ...
Dan Xie, Shing-Tung Yau
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

A scoping review on the potential of three-dimensional bioprinting in auricular cartilage regeneration

SRM Journal of Research in Dental Sciences
Background The human ear significantly influences facial appearance. Auricular abnormalities can arise from many causes, and the cartilage cannot self-regenerate.
Eman Assem Ibrahim, Moamen Mohsen Sarhan, Salah Ezzelarab, Mona K. Marei   +3 more
doaj   +1 more source

Three Dimensional Spheroid Co-culture Invasion Assay

Bio-Protocol, 2015
The assay was developed to investigate the impact of stromal cells of different types (in our case breast cancer associated fibroblasts stably manipulated to modify expression of genes of interest) on the invasive capacity of epithelial cancer cells (in ...
Eldo Verghese, Eldo Verghese
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Three Dimensional Printing in Orthopaedic Surgery

Orthopaedic Journal of Sports Medicine, 2016
Objectives: Three dimensional (3D) printing technology has many current and future applications in orthopaedics. The objectives of this article are to review published literature regarding applications of 3D technology in orthopaedic surgery with a focus
Jonathan Mulford, N MacKay, S Babazadeh
doaj   +1 more source

Three-dimensional Echocardiography

European Cardiology Review, 2006
Although two-dimensional echocardiography (2DE) was a major step forward for the noninvasive assessment of cardiac structure and function, the diagnosis of complex disorders remained a difficult mental conceptualization process. In addition, the measurement of left ventricular volume and function, the most common referral reason for echocardiography ...
openaire   +1 more source