Results 61 to 70 of about 562,100 (312)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Algebra of Three Dimensional Geometric Filters and its Relevance in 3-D Image Processing

The International journal of Multimedia & Its Applications, 2012
This paper gives a novel concept of what we call as Geometric Filters defined over a 3-D rectangular grid of pixels. These G-Filters have potential applications to processing of volumetric images. In addition, the paper describes in brief the algebra of G-Filters by formulating a lattice of convex polyhedrons (structuring elements) constructed in a ...
openaire   +1 more source

Three-dimensional (3-D) seismic imaging of conduits and radial faults associated with hydrothermal vent complexes (Vøring Basin, Offshore Norway) [PDF]

Marine Geology, 2018
Here, we document a suite of radial faults associated with hydrothermal vent complexes in the Vøring Basin, offshore Norway. These complexes have pyramid-shaped, cylindrical- and conical-shaped conduits, with a dome-, or eye-shaped morphology at their summit, intruding on Paleogene sedimentary rocks.
Omosanya, Kamaldeen O., Eruteya, Ovie E., Siregar, Einstein S.A., Zieba, Krzysztof J., Johansen, Ståle E., Alves, Tiago, Waldmann, Nicolas D.   +6 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The use of GPR to image three-dimensional (3-D) turbidite channel architecture in the Carboniferous Ross Formation, County Clare, western Ireland [PDF]

Geological Society, London, Special Publications, 2003
Abstract Petroleum reservoir models are currently built from two-dimensional (2-D) information. An understanding of both the large-scale and internal three-dimensional (3-D) architecture of turbidite channel deposits is important for both hydrocarbon exploration and production. A ground penetrating radar (GPR) survey was undertaken on a study
Pringle, JK, Clarke, JD, Westerman, AR, Gardiner, AR   +3 more
openaire   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Bayesian 3-D interferometric ISAR imaging for the targets with limited pulses

The Journal of Engineering, 2019
It is difficult to yield high azimuth resolution of a target in short coherent processing interval, which brings certain challenges for the subsequent three-dimensional (3-D) interference inverse synthetic aperture radar (InISAR) imaging.
Xuefei Chen, Yong Wang
doaj   +1 more source