Results 61 to 70 of about 632,952 (333)

Similarity Measurement and Retrieval of Three-Dimensional Voxel Model Based on Symbolic Operator

ISPRS International Journal of Geo-Information
Three-dimensional voxel models are widely applied in various fields such as 3D imaging, industrial design, and medical imaging. The advancement of 3D modeling techniques and measurement devices has made the generation of three-dimensional models more ...
Zhenwen He, Xianzhen Liu, Chunfeng Zhang
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Multiplane 3D superresolution optical fluctuation imaging [PDF]

, 2013
By switching fluorophores on and off in either a deterministic or a stochastic manner, superresolution microscopy has enabled the imaging of biological structures at resolutions well beyond the diffraction limit.
Bocchio, Noelia L., Dubikovskaya, Elena A., Geissbuehler, Stefan, Godinat, Aurélien, Lasser, Theo, Leutenegger, Marcel, Sharipov, Azat   +6 more
core   +1 more source

Revealing three-dimensional structure of individual colloidal crystal grain by coherent x-ray diffractive imaging [PDF]

, 2016
We present results of a coherent x-ray diffractive imaging experiment performed on a single colloidal crystal grain. The full three-dimensional (3D) reciprocal space map measured by an azimuthal rotational scan contained several orders of Bragg ...
Dronyak, R., Dzhigaev, D., Gorobtsov, O. Y., Gulden, J., Kalbfleisch, S., Kurta, R. P., Lorenz, U., Meijer, J. M., Petukhov, A. V., Physical and Colloid Chemistry, Shabalin, A. G., Singer, A., Sprung, M., Sub Physical and Colloid Chemistry, Vartanyants, I. A., Yefanov, O. M., Zozulya, A. V.   +16 more
core   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

System- and sample-agnostic isotropic three-dimensional microscopy by weakly physics-informed, domain-shift-resistant axial deblurring

Nature Communications
Three-dimensional subcellular imaging is essential for biomedical research, but the diffraction limit of optical microscopy compromises axial resolution, hindering accurate three-dimensional structural analysis.
Jiashu Han, Kunzan Liu, Keith B. Isaacson, Kristina Monakhova, Linda G. Griffith, Sixian You   +5 more
doaj   +1 more source

Compressive Spectral Imaging with Diffractive Lenses

, 2019
Compressive spectral imaging enables to reconstruct the entire three-dimensional (3D) spectral cube from a few multiplexed images. Here, we develop a novel compressive spectral imaging technique using diffractive lenses.
Kar, Oğuzhan Fatih, Oktem, Figen S.
core   +1 more source

Three-dimensional photoacoustic tomography based on the focal-line concept [PDF]

, 2011
A full ring ultrasonic array-based photoacoustic tomography system was recently developed for small animal brain imaging. The 512-element array is cylindrically focused in the elevational direction, and can acquire a two-dimensional (2D) image in 1.6 s ...
Aguirre, Andres, Guo, Zijian, Maslov, Konstantin, Percival, Christopher, Wang, Lihong V., Xia, Jun, Zhu, Quing   +6 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Two-photon imaging through a multimode fiber

, 2015
In this work we demonstrate 3D imaging using two-photon excitation through a 20 cm long multimode optical fiber (MMF) of 350 micrometers diameter.
Morales-Delgado, Edgar E., Moser, Christophe, Psaltis, Demetri   +2 more
core   +1 more source