Results 91 to 100 of about 1,146,771 (321)

Three-Dimensional Image and Video Processing

open access: yesEURASIP Journal on Image and Video Processing, 2008
EURASIP Journal on Image and Video Processing ...
Eisert, Peter   +2 more
openaire   +5 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Asymmetrical Three-Dimensional Conformal Imaging Lens

open access: yesPhotonics
Absolute instrument refers to a media that can make light rays to propagate in a closed orbit and perform imaging and self-imaging. In the past few decades, traditional investigations into absolute instrument have been centered on the two-dimensional ...
Desen Gong   +3 more
doaj   +1 more source

Three-dimensional visualisation of tracks in OPERA nuclear emulsion films [PDF]

open access: yes, 2005
The possibility of a three-dimensional visualisation/reconstruction of tracks in nuclear emulsion films using X-ray imaging is described in this paper.
Damet, Jerome   +2 more
core   +3 more sources

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause   +6 more
wiley   +1 more source

Application of Three-Dimensional Volumetric Ultrasonography in Patients with Bladder Cancer and Its Mimickers: A Pictorial Essay

open access: yes대한영상의학회지, 2017
Various diseases of the urinary bladder can be demonstrated as being polypoid, a nodular bladder mass or as focal bladder wall thickening. This includes malignant or benign neoplasms, urinary stones, or other inflammatory bladder conditions.
Sujin Ko   +3 more
doaj   +1 more source

Refractive Index Matched Scanning and Detection of Soft Particle

open access: yes, 2017
We describe here how to apply the three dimensional imaging technique of refrecative index matched scanning to hydrogel spheres. Hydrogels are water based materials with a low refractive index, which allows for index matching with water-based solvent ...
Behringer, R. P.   +2 more
core   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

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