Results 41 to 50 of about 13,706,163 (294)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A numerical study of strained three-dimensional wall-bounded turbulence
Channel flow, initially fully developed and two-dimensional, is subjected to mean strains that emulate the effect of rapid changes of streamwise and spanwise pressure gradients in three-dimensional boundary layers, ducts, or diffusers.
Coleman, G.N., Spalart, P.R., Kim, J.
core +1 more source
Three dimensional lung models - Three dimensional extracellular matrix models
In vitro models for investigating mechanisms underlying repair and regeneration in lung disease have advanced greatly in the last decades. Of these models, three-dimensional (3D) models are particularly interesting, owing to their enhanced resemblance of the physiological conditions in vivo.
Nizamoglu, Mehmet +7 more
openaire +2 more sources
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
A MODEL OF THREE-DIMENSIONAL LATTICE GRAVITY [PDF]
A model is proposed which generates all oriented 3D simplicial complexes weighted with an invariant associated with a topological lattice gauge theory. When the gauge group is SUq(2), qn=1, it is the Turaev-Viro invariant and the model may be regarded as a nonperturbative definition of 3D simplicial quantum gravity. If one takes a finite Abelian group
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Building Three Dimensional Head Models
Summary: This paper proposes a camera-based real-time system for building a three-Dimensional (3D) human head model. The proposed system is first trained in a semiautomatic way to locate the user's facial area and is then used to build a 3D model based on the front and profile views of the user's face. This is achieved by directing the user to position
Nikolaos Sarris +2 more
openaire +3 more sources

