Results 51 to 60 of about 13,706,163 (294)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Efficient three-dimensional modelling of high-rise building structures
Journal of Civil Engineering and Management, 2013 A multi-storey building is habitually modelled as a frame structure which neglects the shear wall/slab openings along with the inclusion of staircases. Furthermore, the structural strength provided by shear walls and slabs is not precisely incorporated ...
Mohammed Jameel +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Micromagnetic studies of three-dimensional pyramidal shell-structures [PDF]
, 2010 In this article we present a systematic, numerical analysis of the magnetic properties of pyramidal-shaped core-shell structures in a size range below 400nm.These are three dimensional structures consisting of a ferromagnetic shell which is grown on top ...
Knittel, Andreas +5 more
core +2 more sources
Інформаційні технології і засоби навчання, 2017 The article is devoted to some aspects of the formation of future bachelor's graphic competence in computer sciences while teaching the fundamentals for working with three-dimensional modelling means.
Kateryna P. Osadcha, Hanna Yu. Chemerys
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Extreme-Point-based Heuristics for the Three-Dimensional Bin Packing problem [PDF]
, 2008 One of the main issues in addressing three-dimensional packing problems is finding an efficient and accurate definition of the points at which to place the items inside the bins, because the performance of exact and heuristic solution methods is actually
CRAINIC T. G +3 more
core +1 more source
Numerical modelling of three-dimensional sinkhole stability using finite different method
, 2021 The stability of a cavity underlying homogeneous clay in an unsupported greenfield condition is examined in this paper using the finite difference program, FLAC.
Shiau, Jim, Mirza Hassan, Mohammad
core +1 more source
Three-dimensional numerical modelling of random fibrous networks
Fibrous networks can be found in both natural and artificial systems. This study puts forward an efficient and accurate numerical method which is useful to model fibrous networks in three-dimensional (3D) space.
Emrah Demirci (1256556) +2 more
core +5 more sources