Results 61 to 70 of about 21,357,317 (281)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Analysis of spatial thermal field in a magnetic bearing

Open Physics, 2018
This paper presents two mathematical models for temperature field analysis in a new hybrid magnetic bearing. Temperature distributions have been calculated using a three dimensional simulation and a two dimensional one.
Wajnert Dawid, Tomczuk Bronisław
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

MHD THREE-DIMENSIONAL STAGNATION-POINT FLOW OF A MICROPOLAR FLUID [PDF]

, 2011
The steady three-dimensional stagnation-point flow of an electrically conducting micropolar fluid in the absence and in the presence of a uniform external electromagnetic field (E0,H0) is analyzed and some physical situations are examined. In particular,
Giantesio, Giulia, Borrelli, Alessandra, Patria, Maria Cristina   +2 more
core  

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

A three-dimensional analytical solution of the microheater temperature before bubble nucleation

, 2008
A three-dimensional analytical solution of the microheater temperature based on heat diffusion equation is developed and compared with experimental results. Dimensionless parameters are introduced to analyze the temperature rise time and the distribution
Tang, Q. H., Xu, J. L.
core   +1 more source

Phase-field Simulation and Experimental Validation on Microstructure Evolution of Fe-1.5% C Alloy [PDF]

Teshugang
Two-dimensional and three-dimensional phase field models were constructed using KKS model to investigate the three-dimensional microstructure growth mechanism of Fe-1.5% C alloy during solidification.Through high-temperature laser confocal technology， in-
Gao Ting, Li Wanming, Wang Zhanzhong
doaj   +2 more sources

Multifield Calculation and Analysis of Excitation Winding Interturn Short Circuit Fault in Turbo-Generator

Energies, 2018
Excitation winding interturn short circuit (EWISC) is a common fault in turbo-generators. Once the fault occurs, if not handled in time, it will result in significant security risks to the power system.
Minghan Ma, Yonggang Li, Yucai Wu, Chenchen Dong   +3 more
doaj   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source