Results 41 to 50 of about 95,337 (259)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Three-dimensional Velocity Structure Beneath Guangzhou, China, Derived from Synchronous and Asynchronous Ambient Noise Tomography

CT Lilun yu yingyong yanjiu
Located at the northern margin of the Pearl River Delta, Guangzhou is characterized by complex subsurface structures resulting from the intersection of multiple active faults, leading to elevated geohazard risks.
Jiaxin HE, Xinlei SUN, Jianye ZONG, Yu ZHU, Yusong SHEN   +4 more
doaj   +1 more source

A Backus--Gilbert approach to inversion of travel-time data for three-dimensional velocity structure [PDF]

Geophysical Journal International, 1979
Summary. Considerable effort has recently been directed towards constructing three-dimensional velocity models to fit seismic traveltime data. Most studies have involved parameterizing the model by a limited number of boxes within which the velocity is assumed constant.
Chou, Chee W., Booker, John R.
openaire   +2 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

THREE-DIMENSIONAL STRUCTURE OF THE CENTRAL REGION OF NGC 7027: A QUEST FOR TRAILS OF HIGH-VELOCITY JETS [PDF]

The Astronomical Journal, 2010
We report on the results of a radio interferometric observation of NGC7027 in the CO J=2-1 and 13CO J=2-1 lines. The results are analyzed with morpho-kinematic models developed from the software tool Shape. Our goal is to reveal the morpho-kinematic properties of the central region of the nebula, and to explore the nature of unseen high-velocity jets ...
Zhang, Y, Kwok, SUN, Nakashima, JI, Koning, N   +3 more
openaire   +4 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

An Entropic Model for the Assessment of Streamwise Velocity Dip in Wide Open Channels

Entropy, 2018
The three-dimensional structure of river flow and the presence of secondary currents, mainly near walls, often cause the maximum cross-sectional velocity to occur below the free surface, which is known as the “dip” phenomenon.
Domenica Mirauda, Marilena Pannone, Annamaria De Vincenzo   +2 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Data on samara morphology and wind dispersal in the invasive tree Ailanthus altissima

Data in Brief, 2019
The data presented in this paper is supporting the research article “Estimating wind dispersal potential in Ailanthus altissima: The need to consider the three-dimensional structure of samaras” [1].
Greg Planchuelo, Pablo Catalán, Juan A. Delgado, Antonio Murciano   +3 more
doaj   +1 more source