Results 111 to 120 of about 24,831,400 (287)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Three-level binary logistic regression outputs for irrigation, fertilization, and pesticide application.

open access: yes, 2019
Three-level binary logistic regression outputs for irrigation, fertilization, and pesticide application.
J. Morgan Grove (7860899)   +14 more
core   +1 more source

A new neutral-point voltage balance modulation strategy for three-level converters

open access: yes机车电传动
Three-level converters have been widely used in high-power rail transit applications due to their advantages. However, they also have an inherent problem of neutral-point voltage imbalance. To address this issue in neutral point clamped (NPC) converters,
ZHANG Hu   +3 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Three-level DPC model learns progressively more abstract temporal representations.

open access: yes
(a) Generative model for three-level DPC. (b) Schematic depiction of an inference process. Observation nodes are omitted for clarity. (c) Inference for an example Moving MNIST sequence with “straight bouncing” dynamics.
Linxing Preston Jiang (17936170)   +1 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigation of Constant SVPWM and Variable RPWM Strategies on Noise Generated by an Induction Motor Powered by VSI Two- or Three-Level

open access: yesApplied Sciences
A three-phase inverter generates non-sinusoidal voltages, contains high order harmonics, and concentrates on switching frequency multiples. Supplying an induction machine (IM) with a voltage source inverter (VSI) increases the acoustic noise content ...
Bouyahi Henda, Adel Khedher
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Monthly sea level from coastal tide gauge station Puerto_Madero, 1986-1988 (Research quality database)

open access: yes, 2006
Monthly sea level from coastal tide gauge station Puerto_Madero, 1986-1988 (Research quality ...
WOCE Sea Level, WSL   +1 more
core   +1 more source

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