Results 121 to 130 of about 24,831,400 (287)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Identifying urban rewilding opportunity spaces in a metropolis: Chongqing as an example

open access: yesEcological Indicators
The worldwide urbanization has resulted in a massive loss of natural habitats, which is threatening biodiversity and socio-ecological sustainability.
Xiaodong Jin, Shenhua Qian, Jia Yuan
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Monthly fast delivery sea level from coastal tide gauge station Kanton-B, 1985-2001

open access: yes, 2006
Monthly fast delivery sea level from coastal tide gauge station Kanton-B, 1985 ...
WOCE Sea Level, WSL   +1 more
core   +1 more source

Design of a Tri-linked Symmetry IGCT Phase Module with Compact Structure

open access: yesKongzhi Yu Xinxi Jishu, 2015
It designed a tri-linked structural symmetry IGCT phase module based on NPC three-level circuit with high density and high reliability. Its electrical design, press mounting design and water-cooling design are highly integrated within one unit.
LI Yanyong, HU Jiaxi, SUN Baotao
doaj  

Rethinking Obesity Through the Lens of Lipid Spillover

open access: yesJACC: Basic to Translational Science
Summary: Conventional models frame obesity as excess caloric intake but do not explain why cardiometabolic disease develops in only a subset of individuals.
Shaun Khanna, MBBS, MMed   +2 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Monthly sea level from coastal tide gauge station Cendering, 1984-2001 (Research quality database)

open access: yes, 2006
Monthly sea level from coastal tide gauge station Cendering, 1984-2001 (Research quality ...
WOCE Sea Level, WSL   +1 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Texas Low-Level Radioactive Waste Disposal Facility Conceptual Design, December 1983

open access: yes, 1983
Report of the design of a low-level radioactive waste disposal facility and summarized information relating to the infrastructure and how it will ...
Texas Low-Level Radioactive Waste Disposal Authority
core  

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