Results 31 to 40 of about 84,923 (263)

INVERSE MODEL OF DISPLACEMENT FOR THREE-POINT BENDING TEST

open access: yes, 2021
Three-point bending is an important test for various parameters in material science. In order to validate our layered fracture model we need a relationship between the loading force and the displacement.
Kožar, Ivica   +3 more
openaire   +1 more source

Three point bend creep testing of carbon/epoxy [PDF]

open access: yes, 1990
This study provides data to verify theoretical models for predicting and characterizing viscoelastic behavior of fiber composites. Since performing uninterrupted creep tests for years at a time was not feasible, creep behavior was accelerated with elevated temperatures.
openaire   +2 more sources

αSiC - βSiC - graphene composites

open access: yesScientific Reports, 2023
In this study, the mechanical properties of the pressureless sintered samples of α-SiC based composite containing 0–3 wt.% graphene and 0–15 wt.% nano β-SiC were investigated. Simultaneous usage of nano β-SiC and graphene and transformation of β-SiC (3C)
Ali Razmjoo   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Three-Point Bending Fatigue Test of TiAl6V4 Titanium Alloy at Room Temperature

open access: yesAdvances in Materials Science and Engineering, 2019
A polycrystalline alpha-beta TiAl6V4 alloy in the annealed condition was used for the three-point bending fatigue test at frequency f∼100 Hz. The static preload Fstat. = −15 kN and variable dynamic force Fdyn. = −7 kN to −13.5 kN were set as fatigue test
Juraj Belan   +3 more
doaj   +1 more source

Study of mechanisms of crack formation on tungsten composites using the three-point method

open access: yesVìsnik Harkìvsʹkogo nacìonalʹnogo unìversitetu ìmenì V.N. Karazìna. Serìâ: fìzika., 2022
The aim of this study was evaluated the ductile-to-brittle transition temperature (DBTT) and microstructure of miniaturized tungsten composites by three point bending method.
M.V. Lebedieva   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

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