Results 121 to 130 of about 2,239,326 (300)

Meglumine-Promoted Eco-Compatible Pseudo-Three-Component Reaction for the Synthesis of 1,1-Dihomoarylmethane Scaffolds and Their Green Credentials. [PDF]

ACS Omega, 2022
Patel MS, Parekh JN, Chudasama DD, Patel HC, Dalwadi P, Kunjadiya A, Bhatt V, Ram KR.   +7 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Catalyst-Controlled Selectivity Switch in Three-Component Reaction: An NHC-Catalyzed Strategy for the Synthesis of δ-Lactone-Fused Spirobenzofuran-3-ones. [PDF]

Molecules, 2022
Wang Z, Yang T, Liu D, Chen R, Wang N, Liu H, Li J, Wang K, Liu H.   +8 more
europepmc   +1 more source

On analysis of chemical reactions coupled gas flows in SOFCs [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Sunden, B, Yang, G, Yuan, J   +3 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Sequential Carboborylation–Suzuki Coupling of α,β‐Unsaturated Tosylhydrazones: A Dual CC Bond‐Forming Strategy for Molecular Diversification

ChemistryEurope
The one‐pot three‐component process involving N‐tosylhydrazones derived from cyclic α,β‐unsaturated ketones, alkylboronic acids, and aryl halides is reported.
Álvaro Valdés‐Maqueda, Manuel Plaza, Carlos Valdés   +2 more
doaj   +1 more source

Asymmetric synthesis of quaternary aryl amino acid derivatives via a three-component aryne coupling reaction

Beilstein Journal of Organic Chemistry, 2011
A method was developed for the synthesis of α-alkyl, α-aryl-bislactim ethers in good to excellent yields and high diastereoselectivities, consisting of a facile one-pot procedure in which the aryl group is introduced by means of a nucleophilic addition ...
Elizabeth P. Jones, Peter Jones, Andrew J. P. White, Anthony G. M. Barrett   +3 more
doaj   +1 more source

Copper-catalyzed three-component reaction to synthesize polysubstituted imidazo[1,2-a]pyridines. [PDF]

RSC Adv, 2022
Zhou Z, Luo D, Li G, Yang Z, Cui L, Yang W.   +5 more
europepmc   +1 more source

Factors Affecting the Impact of CAP Scenarios on Farm Structure: An Analysis Based on Stated Intentions [PDF]

Several authors have emphasised the effect of agricultural policy (such as SFP) as a driver of structural change. This paper aims to identify the determinants of the change in the use of productive factors under different policy scenarios.
Bartolini, Fabio, Viaggi, Davide
core   +1 more source

Three-body Coulomb breakup of 11Li in the complex scaling method

, 2003
Coulomb breakup strengths of 11Li into a three-body 9Li+n+n system are studied in the complex scaling method. We decompose the transition strengths into the contributions from three-body resonances, two-body ``10Li+n'' and three-body ``9Li+n+n ...
Aguilar, Aoyama, Audi, Balslev, Berggren, Bertulani, Furutani, Garrido, Hansen, Ieki, Ikeda, Katō, Katō, Kiyomi Ikeda, Kiyoshi Katō, Kukulin, Mukai, Myo, Myo, Myo, Nakamura, Sackett, Saito, Shigeyoshi Aoyama, Shimoura, Takayuki Myo, Tang, Tanihata, Tanihata, Tosaka, Tostevin, Zhukov, Zinser   +32 more
core   +1 more source