Results 71 to 80 of about 2,239,326 (300)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Salicylic Acid-catalyzed Three-component Synthesis of 1-Amido/thioamidoalkyl-2-naphthols Under Solvent-free Conditions

open access: yesOrbital: The Electronic Journal of Chemistry, 2019
A simple, efficient, and green procedure for the solvent-free synthesis of 1-amido/thioamidoalkyl-2-naphthols by one-pot stirring of starting reactants at 100 °C has been introduced.
Hassan Darbandi, Hamzeh Kiyani
doaj   +3 more sources

A Hopf Bifurcation in a Three-Component Reaction-Diffusion System with a Chemoattraction

open access: yesAbstract and Applied Analysis, 2013
We consider a three-component reaction-diffusion system with a chemoattraction. The purpose of this work is to analyze the chemotactic effects due to the gradient of the chemotactic sensitivity and the shape of the interface.
YoonMee Ham, Sang-Gu Lee, Quoc Phong Vu
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Modeling chemical reactions in rivers: A three component reaction

open access: yesDiscrete & Continuous Dynamical Systems - A, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Li, Congming, Wright, Eric S.
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

ZrOCl2·8H2O: An efficient and recyclable catalyst for the three-component synthesis of amidoalkyl naphthols under solvent-free conditions

open access: yesJournal of Saudi Chemical Society, 2016
An efficient synthesis of amidoalkyl naphthols from the reaction of β-naphthol and various aromatic aldehydes and amides using ZrOCl2·8H2O, an environmentally friendly catalyst under a thermal solvent-free green procedure is described.
S. Sheik Mansoor   +3 more
doaj   +1 more source

Vector-meson contributions do not explain the rate and spectrum in K_L -> pi0 gamma gamma

open access: yes, 2002
We analyze the recent NA48 data for the reaction K_L -> pi0 gamma gamma with and without the assumption of vector meson dominance (VMD). We find that the data is well described by a three-parameter expression inspired by O(p^6) chiral perturbation theory.
A. Alavi-Harati   +32 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The mechanism underlying backward priming in a lexical decision task: Spreading activation versus semantic matching [PDF]

open access: yes, 1998
Koriat (1981) demonstrated that an association from the target to a preceding prime, in the absence of an association from the prime to the target, facilitates lexical decision and referred to this effect as "backward priming".
Brown, C., Chwilla, D., Hagoort, P.
core   +2 more sources

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