Results 81 to 90 of about 2,230,877 (347)

Modeling chemical reactions in rivers: A three component reaction

Discrete & Continuous Dynamical Systems - A, 2001
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Li, Congming, Wright, Eric S.
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Cerium(III) Chloride: A Highly Efficient Reagent for the Synthesis of α‐Aminonitriles [PDF]

, 2007
We report a highly efficient, one‐pot, three‐component condensation of carbonyl compounds, amines, and TMSCN in MeCN; the reaction is significantly promoted by the catalytic amount of cerium(III) chloride at ambient temperature in excellent yields ...
Nanjundaswamy, H.M., Pasha, M.A.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Isocyanide based multicomponent reactions of oxazolidines and related systems [PDF]

, 2010
N-Alkyloxazolidines react in a multicomponent reaction with carboxylic acids and isocyanides to give N-acyloxyethylamino acid amides. The previously reported reaction conditions were improved using a design of experiments approach (DoE).
Diorazio, LJ, Motherwell, WB, Sheppard, TD, Taylor, BA, Waller, RW   +4 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

ZrOCl2·8H2O: An efficient and recyclable catalyst for the three-component synthesis of amidoalkyl naphthols under solvent-free conditions

Journal of Saudi Chemical Society, 2016
An efficient synthesis of amidoalkyl naphthols from the reaction of β-naphthol and various aromatic aldehydes and amides using ZrOCl2·8H2O, an environmentally friendly catalyst under a thermal solvent-free green procedure is described.
S. Sheik Mansoor, K. Aswin, K. Logaiya, S.P.N. Sudhan   +3 more
doaj   +1 more source

Water formation at low temperatures by surface O2 hydrogenation II: the reaction network

, 2010
Water is abundantly present in the Universe. It is the main component of interstellar ice mantles and a key ingredient for life. Water in space is mainly formed through surface reactions.
Acharyya, Acquista, Bandow, Baulch, Bockelée-Morvan, Boogert, C. Romanzin, Catalano, Cooper, Cuppen, Dulieu, Ehrenfreund, Gerakines, Giguère, H. Linnartz, H. M. Cuppen, Hiraoka, Ioppolo, Keyser, Khriachtchev, Lannon, Loeffler, Matar, Miyauchi, Mokrane, Oba, Orkin, Romanzin, S. Ioppolo, Sellevåg, Sivaraman, Tielens, Troe, Tsang, Tschersich, Tschersich, Whittet, Öberg, Öberg   +38 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Resonantly Forced Inhomogeneous Reaction-Diffusion Systems

, 2000
The dynamics of spatiotemporal patterns in oscillatory reaction-diffusion systems subject to periodic forcing with a spatially random forcing amplitude field are investigated.
C. J. Hemming, Gáspár V., R. Kapral
core   +1 more source