Results 71 to 80 of about 451,945 (268)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

ABSOLUTE INSTABILITY OF COMPRESSIBLE THREE-DIMENSIONAL FLOW

TASK Quarterly, 1999
In the present paper the instability character (absolute/convective) of compressible viscous flow around geometries rotating in uniform flow is analysed. The linear local stability theory is used to investigate the boundary layer stability.
EWA TULISZKA-SZNITKO
doaj  

Numerical Simulation of Sand Erosion in a Square-Section 90-Degree Bend

Journal of Fluid Science and Technology, 2008
Sand erosion is a phenomenon whereby solid particles impinging on a wall cause serious mechanical damage to the wall surface. The performance and lifetime of various machines, such as airplanes, ships, gas turbines, and pumps, are severely degraded by ...
Masaya SUZUKI, Kazuaki INABA, Makoto YAMAMOTO   +2 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Numerical Computation of Three Dimensional Viscous Flow of Axial Flow Runner

工程科学与技术, 2006
:In order to enhance design accuracy and performance，three dimensional viscous flow inside axial flow runner is simulated based on time averaged Navier-Stokes equations, standard k-ε turbulence model, and SIMPLEC algorithm. Predicted efficiency of axial
doaj  

Large-Scale Simulation of Full Three-Dimensional Flow and Combustion of an Aero-Turbofan Engine on Sunway TaihuLight Supercomputer. [PDF]

Entropy (Basel), 2023
Xu Q, Ren H, Gu H, Wu J, Wang J, Xie Z, Yang G.   +6 more
europepmc   +1 more source

Singularities of Three-Dimensional Ricci Flows

, 2016
The Ricci flow is an evolution of a Riemannian metric driven by a parabolic PDEs and was introduced by Hamilton in 1982. It has been the fundamental tool for some important achievements in geometry in the early 2000s, such as Perelman’s proof of the geometrization conjecture and Brendle–Schoen’s proof of the differentiable sphere theorem.
openaire   +3 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

A three-dimensional flow model of screen channel liquid acquisition devices for propellant management in microgravity. [PDF]

NPJ Microgravity, 2022
Wang Z, Yang G, Wang Y, Jin X, Zhuan R, Zhang H, Wu J.   +6 more
europepmc   +1 more source