Results 111 to 120 of about 33,716,273 (299)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Three-Phase Fuzzy Feeder Models for Fast Distribution System Calculations

, 2012
[[abstract]]Based on fuzzy set theory, this study introduces three novel three-phase fuzzy feeder models for fast distribution system calculations. These fuzzy models are formulated using three lumped individual phase loads to represent single-phase ...
Wang, Shyi-Wen; Huang, Wei-Tzer
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Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation? [PDF]

, 2018
BACKGROUND: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC) measured the global prevalence of symptoms of asthma in children.
Charlotte E. Rutter, David P. Strachan, Garcia-Marcos, L, Rutter, Charlotte E, Silverwood, Richard J, Richard J. Silverwood, Neil Pearce, Asher, M Innes, Asher, MI, ISAAC Phase Three Study Group., Pérez-Yarza Pérez-Irezabal, Gorka, González Díaz, Carlos, Mitchell, EA, Strachan, DP, Pearce, Neil, Garcia-Marcos, Luis, Pearce, N, M. Innes Asher, Silverwood, RJ, Strachan, David P, Edwin A. Mitchell, Chiarella, Pascual, Rutter, CE, Mitchell, Edwin A, Luis Garcia‐Marcos, ISAAC Phase Three Study Group, Barba, S., Mallol, J, Gonzalez Diaz, C, Babu, PS Suresh, Gomez, M., Trakultivakorn, M., Ferguson, A, Rennie, D., Romieu, I, Konthen, P, Strachan, D, Amarales, L., Sole, D, de Freitas Souza, L., Joshi, M. K., Montefort, S, Aristizabal, G, Sukumaran, T., Iosefa, T, Vichyanond, P, Imanalieva, C., Aguilar, P, Koffi, B. N., Shah, J., Sabir, M, Standring, P., Singh, V., Gomez, M, Blanco-Quiros, A, al-Momen, JA, Novak, Z, Barragan-Meijueiro, M., Pinto, J Rosado, Mitchell, Edwin A., Ordonez, G. A., Jain, K. C., Kuaban, C, Musa, O. A., Burr, M., Lee, B. W., Pinto-Vargas, R, Suprihati, W, Cua-Lim, F., Linares-Zapien, FJ, Weyler, J, Amarales, L, Merida-Palacio, JV, Chiarella, P., Sa'aga-Banuve, R, Asher, M. I., Bouayad, Z., de Bruyne, J, Cukier, G., Khatav, V. A., Bustos, C, Mohammad, Y, Mohammad, S, Sears, M, Rutter, Charlotte E., Carvajal-Uruena, I, Robertson, CF, E Vlaski, Goh, DY, Quah, BS, Lopes dos Santos, JM, Nishima, S, Mantri, S. N., Trakultivakorn, M, Sa'aga-Banuve, R., Sears, M., Linares-Zapien, F. J., Goh, D. Y., da Cunha, AJ, Odhiambo, J., Cua-Lim, F, Sole, D., von Mutius, E., da Cunha, A. J., Hanumante, N. M., Strachan, David P., Kudzyte, J., Gonzalez-Diaz, S. N., Pearce, N., Contreras, A., Sharma, SK, Garcia-Marcos, L., Chen, Y-Z, Ait-Khaled, N., Anderson, R., Odajima, H, Lis, G, Aristizabal, G., Masjedi, MR, Windom, H. H., Lapides, MC, Tuuau-Potoi, N, de Bruyne, J., Morales-Suarez-Varela, M, Novak, Z., Weyler, J., Breborowicz, A, Musa, OA, de Freitas Souza, L, Forastiere, F, Perez-Yarza, E. G., Crane, J., Lai, C. K. W., von Mutius, E, Quah, B. S., Setty, G, Zar, HJ, Busquets, R. M., Howitt, ME, Vichyanond, P., Al-Rawas, O., the ISAAC Phase Three Study Group (A Brêborowicz, G Lis, R Câmara, ML Chiera, JM Lopes dos Santos, C Nunes, J Rosado Pinto, E Vlaski, P Fuimaono V Pisi, G Wong, DY Goh, HJ Zar, HB Lee, RM Busquets, I Carvajal‐Urueña, G García‐Hernández, L García‐Marcos, C González Díaz, A López‐Silvarrey Varela, M Morales‐ Suárez‐Varela, EG Pérez‐Yarza, OA Musa), Holgado, D., Benavides, LA, Masjedi, M. R., Garcia-Hernandez, G., Lee, BW, Babu, P. S. Suresh, Aguirre, V., Nunes, C., Wong, G, Moyes, C., Baena-Cagnani, CE, Joshi, MK, Cukier, G, Beasley, R, Zhong, N. S., Teh, K. H., Breborowicz, A., Carvajal-Uruena, I., Baratawidjaja, K., Hypolite, IE, Fuimaono, P., Rego, S, El Sony, A., Baeza-Bacab, M, Cepeda, AM, Pekkanen, J, Salvi, S, Steriu, A., Merida-Palacio, J. V., Cepeda, A. M., Zar, H. J., Pattemore, P, Riikjarv, M-A, Bhave, S., Lopez-Silvarrey, A, Beasley, R., Onadeko, B. O., Del-Rio-Navarro, B. E., Flohr, C., Pinto, J. Rosado, Ellwood, P, Setty, G., Lee, HB, al-Momen, J. A., MacKay, R., Konthen, P., Ramirez-Chanona, N, Williams, HC, Huang, JL, Rennie, D, Huang, J. L., Vlaski, E, Howitt, M. E., Ramirez-Chanona, N., Kao, CC, Fuimaono, P, Singh, V, Jain, KC, Bjorksten, B., Al-Rawas, O, Iosefa, T., Aldrey, O, Clayton, TO, Kartasasmita, CB, Garcia-Hernandez, G, Bustos, C., Pherwani, A. V., Weiland, SK, Suprihati, W., Zhong, NS, Rego, S., Bouayad, Z, Camara, R, Perez-Yarza, EG, Chiera, ML, Kunii, O, Khatav, VA, Gonzalez Diaz, C., Windom, HH, Pattemore, P., Ordonez, GA, Aldrey, O., Flohr, C, Lai, C. K., Lis, G., Pisi, V., Vlaski, E., Weinmayr, G, Tuuau-Potoi, N., Romero-Tapia, S, Camara, R., Silverwood, Richard J., El Sony, A, Awasthi, S., Stewart, AW, Mohammad, S., Kao, C. C., Aguirre, V, Anderson, R, Robertson, C. F., Pisi, V, Romieu, I., Sabir, M., Weiland, S. K., Strachan, D., Foliaki, S., Kartasasmita, C. B., Baratawidjaja, K, Moyes, C, Contreras, A, Odhiambo, J, Kudzyte, J, Onadeko, BO, Keil, U., Lapides, M. C., Melaku, K, Morales-Suarez-Varela, M., Clayton, T. O., Nunes, C, Brunekreef, B., Pan, Li, Chiera, M. L., Asher, M. Innes, Aguilar, P., Benavides, L. A., Gonzalez-Diaz, SN, Tabbah, K., Kunii, O., Lee, H. B., Zsigmond, G., Garcia-Almaraz, R., Wong, G., Anderson, HR, Baena-Cagnani, C. E., Nishima, S., Sukumaran, T, Pekkanen, J., Holgado, D, Hanumante, NM, Pherwani, AV, Hypolite, I. E., Koffi, BN, Forastiere, F., Anderson, H. R., Del-Rio-Navarro, BE, Mohammad, Y., Lai, CKW, Mallol, J., Bhave, S, Odajima, H., Baeza-Bacab, M., Blanco-Quiros, A., Kuaban, C., Ferguson, A., Awasthi, S, Williams, H. C., Tabbah, K, Barba, S, Bjorksten, B, MacKay, R, Busquets, RM, Montefort, S., Sharma, S. K., Chiarella, P, Lopez-Silvarrey, A., Pinto-Vargas, R., Brunekreef, B, Zsigmond, G, Imanalieva, C, Shah, J, Steriu, A, Keil, U, Melaku, K., Ait-Khaled, N, Weinmayr, G., Garcia-Almaraz, R, Lai, CK, Romero-Tapia, S., Standring, P, Foliaki, S, Lopes dos Santos, J. M., Barragan-Meijueiro, M, Ellwood, P., Salvi, S., Crane, J, Teh, KH, Burr, M, Mantri, SN, Stewart, A. W., Mitchell, E. A.   +331 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

CONTINUATION POWER FLOW OF AN UNBALANCED THREE-PHASE FOUR-WIRE DISTRIBUTION SYSTEM

Journal of Engineering and Sustainable Development, 2018
A continuation power flow algorithm for an unbalanced three phase four wire distribution system is presented. The proposed algorithm is used to trace the loci of the voltage of the different phases of an unbalanced three-phase distribution system. The
Kassim Abdulrezak Al-Anbarri, Alaa Saad Hussain   +1 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Analysis of Output Current Ripple of Three-phase PWM Inverter under Discontinuous Modulation Techniques [PDF]

, 2010
In this paper, an analysis of output current ripple of three-phase PWM inverters with discontinuous modulation is presented. The analytical expressions for discontinuous modulation injection signal are derived.
Dahono, Pekik Argo
core