TMCO3 as a downstream target of ALKBH5 is found, which regulates its expression in an m6A‐dependent manner, and then a new phosphorylation site on TMCO3 is identified and determines the specific mechanism of TMCO3 with AKT. Moreover, the combined treatment of targeting the TMCO3 and inhibition of AKT in mice models with HCC achieves great results ...
Xinxin Li+8 more
wiley +1 more source
Supplementing low protein diets with methionine or threonine during mixed Eimeria challenge
: We investigated the effects of supplementing low protein diets with methionine (Met) or threonine (Thr) during a mixed Eimeria (consisting of E. acervulina, E. maxima and E. tenella) challenge in broilers. All birds were fed the same starter diet (d1–9)
James Taylor+8 more
doaj
Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu+8 more
wiley +1 more source
The Threonine-Sensitive Homoserine Dehydrogenase and Aspartokinase Activities of Escherichia coli K 12. 4. Isolation, Molecular Weight, Amino Acid Analysis and Behaviour of the Sulfhydryl Groups of the Protein Catalyzing the Two Activities [PDF]
Paolo Truffa‐Bachi+4 more
openalex +1 more source
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu+9 more
wiley +1 more source
Distribution of soluble amino acids in maize endosperm mutants
For human nutrition the main source of vegetable proteins are cereal and legume seeds. The content of total soluble amino acids in mature endosperm of wild-type, opaque and floury maize (Zea mays L.) mutants were determined by HPLC.
Toro Alejandro Alberto+4 more
doaj
Threonine Inhibition in a Strain of Neurospora
C.O. Doudney, R. P. Wagner
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The enzymic formation of aminoacetone from threonine and its further metabolism [PDF]
ML Green, WH ELLIOTT
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Computational predictions identify ethylene glycol and lithium chloride as optimal components for a green deep eutectic solvent (DES). And further investigations determine the optimal reaction conditions and process parameters for DES treatment of spent lithium iron phosphate (S‐LFP).
Yixin Lin+7 more
wiley +1 more source
THE ACCUMULATION OF KETO ACIDS AND ACETALDEHYDE BY A STRAIN OF NEUROSPORA INHIBITED BY THREONINE
R. P. Wagner, Arloa Bergquist
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