Results 201 to 210 of about 611,533 (383)

Lead Dysregulates Serine/Threonine Protein Phosphatases in Human Neurons [PDF]

, 2010
Abdur Rahman, Bruce J. Brew, Gilles J. Guillemin   +2 more
openalex   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

A preliminary study on the early warning role of DL-malic acid in atrial fibrillation occurrence among patients with hyperuricemia. [PDF]

Front Cardiovasc Med
Li D, Jiao H, Liu D, Li Z, Lv S, Jin H, Yan X.   +6 more
europepmc   +1 more source

Additional Serine/Threonine Phosphorylation Reduces Binding Affinity but Preserves Interface Topography of Substrate Proteins to the c-Cbl TKB Domain

, 2010
Qingxiang Sun, Rebecca Jackson, C.W.W. Ng, Graeme R. Guy, J. Sivaraman   +4 more
openalex   +2 more sources

Capsaicin Bioactive in Cabai (Capsicum Annum L.) as Anticancer Through Inhibition of over Ekspresi Protein Target RAC-alpha serine/threonine-protein kinase (AKT1) and Mitogen-activated protein kinase 1 (MAPK1) on Hepatocyt Cell Mice (mus musculus) [PDF]

, 2020
Mohammad Sukmanadi, Sri Agus Sudjarwo, Mustofa Helmi Effendi, Pudji Srianto, A Aulanni’am, Rr. Sri Pantja Madyawati, Mirni Lamid, Hani Plumeriastuti   +7 more
openalex   +1 more source

THE THREONINE REQUIREMENT FOR GROWTH

Journal of Biological Chemistry, 1952
W C, ROSE, R E, KOEPPE, H J, SALLACH
openaire   +2 more sources

Role of eukaryotic-like serine/threonine kinases in bacterial cell division and morphogenesis.

FEMS Microbiology Reviews, 2016
S. Manuse, Aurore Fleurie, L. Zucchini, Christian Lesterlin, C. Grangeasse   +4 more
semanticscholar   +1 more source

TOPK Inhibition Promotes Anti‐Tumor Immunity Via eIF4F Complex Mediated STAT1 Translation in Gastric Cancer

Advanced Science, EarlyView.
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen, Longtao Huangfu, Gangjian Wang, Xueying Wang, Huanbo Zhu, Qian Yao, Cong Chen, Xiaohuan Tang, Ting Guo, Biao Fan, Xingyang Liu, Qingda Li, Zining Liu, Ying Hu, Tianze Sun, Jiafu Ji, Xiaofang Xing   +16 more
wiley   +1 more source

Amino acid metabolism of the thermophilic acetogen Thermacetogenium phaeum. [PDF]

PLoS One
Cai Y, Marquardt A, Schleheck D, Müller N.   +3 more
europepmc   +1 more source

SERS‐AI‐LUA‐Driven Salivary Diagnosis of Head and Neck Cancer Using Graphene‐Assisted Plasmonic Nanocorals

Advanced Science, EarlyView.
The developed graphene‐assisted plasmonic nanocoral platform enables sensitive, label‐free surface‐enhanced Raman scattering analysis of salivary metabolites for head and neck cancer (HNC) detection. When combined with machine learning classification and nonnegative least squares‐based spectral deconvolution, this approach achieves 98% diagnostic ...
Hyo Jeong Seo, Boyou Heo, Jun‐Yeong Yang, Rowoon Park, Sung‐Gyu Park, Jiyoung Yeo, So Hee Park, Chan Kwon Jung, Min‐Young Lee, Jooin Bang, Jun‐Ook Park, Ho Sang Jung   +11 more
wiley   +1 more source