Results 201 to 210 of about 521,154 (335)

GmSop20 Functions as a Key Coordinator of the Oil‐To‐Protein Ratio in Soybean Seeds

open access: yesAdvanced Science, EarlyView.
This study investigates the seed oil‐to‐protein ratio as a comprehensive quality metric and identifies GmSop20 as a crucial regulatory gene through forward genetics methodologies. By integrating GmSop20 with superior haplotypes and using gene editing/overexpression, new strategies are provided for precisely tuning the seed oil‐to‐protein ratio, thereby
Haowei Zheng   +17 more
wiley   +1 more source

Mortalin and PINK1/Parkin‐Mediated Mitophagy Represent Ovarian Cancer‐Selective Targets for Drug Development

open access: yesAdvanced Science, EarlyView.
Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra   +9 more
wiley   +1 more source

Identification and genetic analysis of candidate genes for resistance against <i>Phytophthora sojae</i> in soybean using a genome-wide association study. [PDF]

open access: yesFront Plant Sci
Park HR   +13 more
europepmc   +1 more source

Monitoring the Dynamics of Alzheimer's Disease Biomarkers and the APOE–Tau Axis via Human Cerebral Organoids with Immuno‐SERS

open access: yesAdvanced Science, EarlyView.
Noninvasive and sensitive detection of tau protein dynamics across developmental stages and APOE genotypes remain a challenge in Alzheimer's disease (AD) research. This study reveals the dynamics of tau secretion in label‐free manner using surface‐enhanced Raman spectroscopy (SERS) and human cerebral organoids (hCOs). This study provides novel insights
Yongjae Jo   +11 more
wiley   +1 more source

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