Results 251 to 260 of about 514,103 (332)

Threonine Synthetase Mechanism: Studies with Isotopic Hydrogen

, 1960
Martin Flavin, Clarence Slaughter
openalex   +1 more source

The Link Between TGF‐β Signaling and Chromatin Dynamics Takes an Unexpected Path

BioEssays, EarlyView.
A recent study uncovered a novel mechanism by which Tgfbr1 regulates morphogenesis: not by directly controlling the expression of genes regulating cell fate but by globally modulating chromatin accessibility, thus determining which enhancers are available to other morphogenetic factors, ultimately enabling the activation of specific developmental ...
Moises Mallo
wiley   +1 more source

Evidence supporting a catalytic pentad mechanism for the proteasome and other N-terminal nucleophile enzymes. [PDF]

Nat Commun
Fung D, Razi A, Pandos M, Velez B, Fermin Perez E, Adams L, Rawson S, Walsh RM, Hanna J.   +8 more
europepmc   +1 more source

Dynamic protein interactions probed by NMR spectroscopy

Bulletin of the Korean Chemical Society, EarlyView.
Abstract Dynamic protein–protein interactions are essential for diverse cellular processes but often evade structural characterization due to their transient, heterogeneous, and disordered nature. This review focuses on how nuclear magnetic resonance (NMR) spectroscopy can provide detailed, residue‐level insights into these complex interactions.
Jaeseok Lee, Jung Ho Lee
wiley   +1 more source

STK32C promotes colon tumor progression through activating c-MYC signaling. [PDF]

Cell Mol Life Sci
Zhang X, Jin M, Chu Y, Liu F, Qu H, Chen C.   +5 more
europepmc   +1 more source

Threonine Deaminase from Salmonella typhimurium

, 1968
Mario H. Zarlengo, George W. Robinson, R. O. Burns   +2 more
openalex   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source

Engineering of L-threonine and L-proline biosensors by directed evolution of transcriptional regulator SerR and application for high-throughput screening. [PDF]

Bioresour Bioprocess
Pu W, Feng J, Chen J, Liu J, Guo X, Wang L, Zhao X, Cai N, Zhou W, Wang Y, Zheng P, Sun J.   +11 more
europepmc   +1 more source

The Mechanism of Action of 5'-Adenylic Acid-activated Threonine Dehydrase

, 1968
P.D. Whanger, Allen T. Phillips, K.W. Rabinowitz, Jeanette R. Piperno, J.D. Shada, W.A. Wood   +5 more
openalex   +1 more source

In situ biomimetic materials for dentin repair

BMEMat, EarlyView.
This review primarily discusses the role and clinical application of key biomimetic materials for in situ dentin repair, providing a feasible foundation for future material and performance optimization in situ dentin regeneration. Abstract Dental defects, ranking among the most prevalent diseases globally, pose a serious threat to human health, with ...
Jingjing Deng, Siyi Ren, Xuliang Deng, Yan Wei   +3 more
wiley   +1 more source