Results 271 to 280 of about 514,103 (332)

Two Key Ferredoxins for Nitrogen Fixation Have Different Specificities and Biophysical Properties

Chemistry – A European Journal, EarlyView.
Two ferredoxins, FdC and FdN, are collectively essential for the process of nitrogen fixation by the iron nitrogenase in R. capsulatus. We explore the biophysical factors, through spectroscopic and structural characterizations, which determine ferredoxin functionality and pathway specificity. The structure of FdC (PDB: 9I2A) and model of FdN (AF‐D5ARY6)
Holly Addison, Pascal Pfister, Ana Lago‐Maciel, Tobias J. Erb, Antonio J. Pierik, Johannes G. Rebelein   +5 more
wiley   +1 more source

A Ketol‐Acid Reductoisomerase Inhibitor That Has Antituberculosis and Herbicidal Activity

Chemistry – A European Journal, EarlyView.
1a and 1f are potent inhibitors of ketolacid reductoisomerase (KARI). 1f has good antituberculosis activity and 1a has herbicidal activity against Brassica campestris and Amaranthus retroflexus. Abstract Ketol‐acid reductoisomerase (KARI) is a target for the development of new biocidal agents. This is based on its essential role in branched chain amino
Xin Lin, Julia L. Kurz, Yong‐Hong Li, Shun Jie Wun, Thierry Lonhienne, Ross P. McGeary, Nicholas P. West, Gerhard Schenk, Jian‐Guo Wang, Luke W. Guddat   +9 more
wiley   +1 more source

Phosphorylation of threonine residue in apo-aspartate aminotransferase during the inhibition with N-(pyridoxyl-5′-phosphate)-L-glutamic acid

, 1969
R. M. Khomutov, Severin Se, Elena N. Khurs, N.N. Gulyaev   +3 more
openalex   +1 more source

Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies

Chemistry – A European Journal, EarlyView.
The synthesis of multicomponent cancer vaccines on AuNP carriers could be rationalized by the simultaneous functionalization of the antigen and immunomodulator components on the same particles. Immunization with a “diluted” amount of MUC1‐functionalized AuNPs is still capable of eliciting a strong immune response.
Mattia Ghirardello, Ana Guerreiro, Carmen Bretón, Ismael Compañón, Julio Zabalza, Vincenzo Mangini, Jesús M. Peregrina, Gonçalo J. L. Bernardes, Francisco Corzana   +8 more
wiley   +1 more source

Model-Guided Rational Construction of Escherichia coli Synthetic Consortia for Enhanced 2-Methylbutyric Acid Production. [PDF]

Adv Sci (Weinh)
Liu Y, Xue B, Wang S, Su H.
europepmc   +1 more source

Optical Resolution of DL-Threonine and DL-Allothreonine by the Use of the Oxazolidone Derivatives

, 1961
Toshishige Inui, Takeo Kaneko
openalex   +2 more sources

Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723

Cytoskeleton, EarlyView.
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar, Joyeeta Chakraborty, Pananghat Gayathri, Ramanujam Srinivasan   +3 more
wiley   +1 more source

Exercise Attenuates Skeletal Muscle Atrophy in Senescent SAMP8 Mice: Metabolic Insights from NMR-Based Metabolomics. [PDF]

Molecules
Wu W, Zhang L, Chen Y, Huang C, Yang L, Lin D.   +5 more
europepmc   +1 more source

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

Cytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source

Genetic Variation in the <i>blaZ</i> Gene Leading to the BORSA Phenotype in <i>Staphylococcus aureus</i>. [PDF]

Antibiotics (Basel)
Aarris M, Hertz FB, Nielsen KL, Sato A, Johansen HK, Westh H, Kemp M, Ellermann-Eriksen S, Løbner-Olesen A, Frimodt-Møller N, Charbon G.   +10 more
europepmc   +1 more source